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Antigenic characterization of respiratory syncytial virus associated with acute respiratory infections in Uruguayan children from 1985 to 1987.1985年至1987年乌拉圭儿童急性呼吸道感染相关呼吸道合胞病毒的抗原特征分析。
J Clin Microbiol. 1989 Jul;27(7):1464-6. doi: 10.1128/jcm.27.7.1464-1466.1989.
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A single-season epidemic with respiratory syncytial virus subgroup B2 during 10 epidemic years, 1978 to 1988.1978年至1988年的10个流行年份中,由B2亚组呼吸道合胞病毒引起的单季流行。
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本文引用的文献

1
Occurrence of respiratory syncytial virus subtypes A and B strains in Sweden.瑞典呼吸道合胞病毒A、B亚型毒株的出现情况。
J Med Virol. 1986 Jul;19(3):241-7. doi: 10.1002/jmv.1890190306.
2
Antigenic variation between human respiratory syncytial virus isolates.人呼吸道合胞病毒分离株之间的抗原变异
J Gen Virol. 1986 May;67 ( Pt 5):863-70. doi: 10.1099/0022-1317-67-5-863.
3
Respiratory syncytial virus epidemics: variable dominance of subgroups A and B strains among children, 1981-1986.呼吸道合胞病毒流行情况:1981 - 1986年儿童中A、B亚组毒株的不同优势情况
J Infect Dis. 1988 Jan;157(1):143-8. doi: 10.1093/infdis/157.1.143.
4
Antigenic characterization of respiratory syncytial virus strains with monoclonal antibodies.用单克隆抗体对呼吸道合胞病毒株进行抗原特性分析。
J Infect Dis. 1985 Apr;151(4):626-33. doi: 10.1093/infdis/151.4.626.
5
Preparation and characterization of monoclonal antibodies directed against five structural components of human respiratory syncytial virus subgroup B.针对人呼吸道合胞病毒B亚组五种结构成分的单克隆抗体的制备与鉴定
J Gen Virol. 1987 Dec;68 ( Pt 12):3125-35. doi: 10.1099/0022-1317-68-12-3125.
6
Concurrent circulation of antigenically distinct strains of respiratory syncytial virus during community outbreaks.在社区疫情暴发期间,抗原性不同的呼吸道合胞病毒毒株同时传播。
J Infect Dis. 1986 Feb;153(2):291-7. doi: 10.1093/infdis/153.2.291.
7
Two distinct subtypes of human respiratory syncytial virus.人呼吸道合胞病毒的两种不同亚型。
J Gen Virol. 1985 Oct;66 ( Pt 10):2111-24. doi: 10.1099/0022-1317-66-10-2111.

1985年至1987年乌拉圭儿童急性呼吸道感染相关呼吸道合胞病毒的抗原特征分析。

Antigenic characterization of respiratory syncytial virus associated with acute respiratory infections in Uruguayan children from 1985 to 1987.

作者信息

Russi J C, Delfraro A, Arbiza J R, Chiparelli H, Orvell C, Grandien M, Hortal M

机构信息

Dept. de Laboratorios de S. Publica Ministerio de Salud Publica, Montevideo, Uruguay.

出版信息

J Clin Microbiol. 1989 Jul;27(7):1464-6. doi: 10.1128/jcm.27.7.1464-1466.1989.

DOI:10.1128/jcm.27.7.1464-1466.1989
PMID:2671013
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC267595/
Abstract

The occurrence of subgroup A and B strains of respiratory syncytial virus (RSV) was studied during three epidemic years, 1985 to 1987, in Uruguay. A set of monoclonal antibodies was selected according to their reactivity with local RSV isolates and used for the typing of RSV directly in nasopharyngeal cells by indirect immunofluorescence. Of 77 specimens, 69 could be typed as belonging to subgroup A or B, 5 could not be typed with the restricted set of monoclonal antibodies employed, and 3 reacted with both subgroup-specific antibodies. In 1985 and 1986 subgroup A predominated, accounting for 65.7% of all typed specimens, but in 1987 subgroup B surpassed subgroup A, accounting for 82.4% of the samples.

摘要

1985年至1987年的三年间,在乌拉圭对呼吸道合胞病毒(RSV)A亚组和B亚组毒株的出现情况进行了研究。根据一组单克隆抗体与当地RSV分离株的反应性进行选择,并通过间接免疫荧光法直接在鼻咽细胞中对RSV进行分型。在77份标本中,69份可分型为A亚组或B亚组,5份无法用所使用的有限单克隆抗体组进行分型,3份与两个亚组特异性抗体均发生反应。1985年和1986年A亚组占主导,占所有分型标本的65.7%,但1987年B亚组超过了A亚组,占样本的82.4%。