Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tennodai 1-1-1, Tsukuba, Ibaraki, 305-8577, Japan.
Arch Gerontol Geriatr. 2010 Sep-Oct;51(2):192-8. doi: 10.1016/j.archger.2009.10.007. Epub 2009 Nov 24.
We aimed to compare and identify high and low risk of frailty in community-dwelling older women by using five mobility performance tests. The participants were 166 older women at high risk and 171 age-matched controls at low risk of frailty according to the long-term care insurance (LTCI) system (age: 65-90 years). The mobility performance tests included 5-chair sit-to-stand (STS), alternate step, timed up-and-go (TUG), timed rapid gait (TRG), and usual gait speed (UGS). Data analysis showed that high-risk individuals (81.9%) were more likely to be pre-frail than low-risk individuals (55.0%) by Fried's frailty phenotype. The four mobility performance tests, except the 5-chair STS, had the largest areas under the curve (AUC) for discriminating older women at high and low risk (AUC>0.80, p<0.001). The optimal cutpoint (6 s) for the TRG test had the highest sensitivity (78%) and specificity (83%) in identifying high risk of frailty. Our results suggest that walking ability tests are clinically useful in screening older individuals at high risk of frailty. In particular, the TRG test is more likely than other tests to discriminate older women at high risk of frailty based on the LTCI system.
我们旨在通过五项移动性能测试比较和识别社区居住的老年女性的高风险和低风险脆弱性。参与者为根据长期护理保险(LTCI)系统处于高脆弱性风险的 166 名老年女性和处于低脆弱性风险的 171 名年龄匹配对照者(年龄:65-90 岁)。移动性能测试包括 5 次椅子站立测试(STS)、交替踏步、起立行走计时测试(TUG)、计时快速步态测试(TRG)和通常步态速度测试(UGS)。数据分析显示,高风险个体(81.9%)比低风险个体(55.0%)更有可能通过弗里德的脆弱表型表现为虚弱前期。四项移动性能测试(5 次椅子 STS 除外)在区分高风险和低风险老年女性方面具有最大的曲线下面积(AUC)(AUC>0.80,p<0.001)。TRG 测试的最佳截断点(6 秒)在识别脆弱性高风险方面具有最高的敏感性(78%)和特异性(83%)。我们的研究结果表明,步行能力测试在筛查脆弱性高风险的老年个体方面具有临床意义。特别是,TRG 测试比其他测试更有可能根据 LTCI 系统区分高风险脆弱性的老年女性。