Ananthakrishnan Ashwin N, Issa Mazen, Binion David G
Division of Gastroenterology and Hepatology, Medical College of Wisconsin, Milwaukee, WI, USA.
Med Clin North Am. 2010 Jan;94(1):135-53. doi: 10.1016/j.mcna.2009.08.013.
The past decade has seen an alarming increase in the burden of disease associated with Clostridium difficile. Several studies have now demonstrated an increasing incidence of C difficile infection in patients with inflammatory bowel disease (IBD) with a more severe course of disease compared with the non-IBD population. This article summarizes the available literature on the impact of C difficile infection on IBD and discusses the various diagnostic testing and treatment options available. Also reviewed are clinical situations specific to patients with IBD that are important for the treating physician to recognize.
在过去十年中，与艰难梭菌相关的疾病负担出现了惊人的增长。现在有几项研究表明，炎症性肠病（IBD）患者中艰难梭菌感染的发病率不断上升，与非IBD人群相比，其病程更为严重。本文总结了关于艰难梭菌感染对IBD影响的现有文献，并讨论了各种可用的诊断测试和治疗选择。还回顾了IBD患者特有的临床情况，这些情况对于治疗医生来说很重要，需要加以识别。
