近红外光谱技术在研究早产儿和足月新生儿大脑方面的进展。
Advances in near-infrared spectroscopy to study the brain of the preterm and term neonate.
机构信息
Biomedical Optics Research Laboratory, Clinic of Neonatology, University Hospital Zurich, Frauenklinikstr. 10, 8091 Zurich, Switzerland.
出版信息
Clin Perinatol. 2009 Dec;36(4):807-34, vi. doi: 10.1016/j.clp.2009.07.007.
This article reviews tissue oximetry and imaging to study the preterm and newborn infant brain by near-infrared spectroscopy. These two technologies are now advanced; nearly 100 reports on their use in newborn infants have been published, and commercial instruments are available. The precision of oximetry, however, is a limitation for its clinical use of assessing cerebral oxygenation. Imaging of brain function needs very well defined protocols for sensory stimulation as well as signal analysis to provide meaningful results.
本文通过近红外光谱技术回顾组织血氧测定和成像技术，以研究早产儿和新生儿的大脑。这两项技术现在已经很先进；近红外光谱技术在新生儿中的应用已经发表了近 100 篇报告，并且已经有商业仪器可供使用。然而，血氧测定的精度是其评估脑氧合作用的临床应用的一个限制。脑功能成像需要非常明确的感觉刺激和信号分析协议，以提供有意义的结果。
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