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浙江汉族人群中七个 X 连锁 STR 基因座的等位基因频率。

Allele frequencies of seven X-linked STR loci in Chinese Han population from Zhejiang Province.

机构信息

Department of Criminal Investigation of Zhejiang Provincial Public Security Bureau, 66, Minsheng Road, 310009 Hangzhou, China.

出版信息

Forensic Sci Int Genet. 2009 Dec;4(1):e41-2. doi: 10.1016/j.fsigen.2009.04.005. Epub 2009 May 12.

Abstract

Allele frequencies and forensic parameters of seven X-chromosome STRs (DXS981, DXS7424, DXS101, DXS7133, DXS6789, GATA165B12 and GATA31E08) were estimated from a sample of unrelated individuals (383 females and 313 males) belonging to Chinese Han population in Zhejiang Province, a region located in the east of China. Combining the seven X-linked markers, high mean exclusion chance and power of discrimination values were obtained. Amplification was performed in a single multiplex PCR reaction. Due to the small PCR products (<202bp), the use of these STRs can increase the probability that a degraded sample can be typed.

摘要

从属于中国汉族人群的浙江地区的无关个体(383 名女性和 313 名男性)中,估算了七个 X 染色体 STR(DXS981、DXS7424、DXS101、DXS7133、DXS6789、GATA165B12 和 GATA31E08)的等位基因频率和法医参数。通过将这七个 X 连锁标记组合在一起,获得了较高的平均排除机会和较高的判别能力值。扩增在单个多重 PCR 反应中进行。由于 PCR 产物较小(<202bp),因此使用这些 STR 可以增加对降解样本进行分型的可能性。

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