Freeman H J, Shnitka T K, Piercey J R, Weinstein W M
Gastroenterology. 1977 Dec;73(6):1397-403.
An adult with the late onset immunodeficiency syndrome developed intractable diarrhea. Widespread cytomegalovirus (CMV) infection of the gastrointestinal tract was detected antemortem with detailed morphological studies and viral culture. The CMV-type cells were especially numerous in his severely ulcerated colon. Electron microscopy of infected cells in rectal biopsy material revealed the characteristic features of CMV infection. It is likely that the CMV infection contributed to the symptom complex and the mucosal injury. Unusual opportunistic infections as a cause of diarrhea should be considered in patients with late onset immunodefociency, especially if Giardiasis is ruled out.
一名患有迟发性免疫缺陷综合征的成年人出现了顽固性腹泻。通过详细的形态学研究和病毒培养，生前检测到胃肠道广泛的巨细胞病毒（CMV）感染。在他严重溃疡的结肠中，CMV 型细胞特别多。直肠活检材料中感染细胞的电子显微镜检查揭示了 CMV 感染的特征性表现。CMV 感染很可能导致了症状复合体和黏膜损伤。对于迟发性免疫缺陷患者，尤其是排除贾第虫病的患者，应考虑不寻常的机会性感染作为腹泻的原因。
