Human Performance Laboratory, Department of Kinesiology and Health Education, The University of Texas at Austin, Austin, TX 78712, USA.
Med Sci Sports Exerc. 2010 Mar;42(3):493-8. doi: 10.1249/MSS.0b013e3181b64edd.
Dietary supplementation with polyphenols,particularly ellagitannins, may attenuate the muscular damage experienced after eccentric exercise, producing delayed-onset muscle soreness. The purpose of this study was to determine whether ellagitannin supplementation from Wonderful variety pomegranate extract (POMx) improved recovery of skeletal muscle strength after eccentric exercise.
Recreationally active males were randomized into a crossover design with either pomegranate extract (POMx) or placebo (PLA), each given during a period of 9 d.To produce delayed-onset muscle soreness, subjects performed two sets of 20 maximal eccentric elbow flexion exercises with one arm.Maximal isometric elbow flexion strength and muscle soreness as well as serum measures of creatine kinase, myoglobin, interleukin 6, and C-reactive protein were made at baseline and 2, 24, 48, 72, and 96 h after exercise.
With both treatments, strength was similarly reduced 2 h after exercise (i.e., 72% of baseline), and recovery of strength was incomplete after 96 h (i.e., 91% of baseline).However, strength was significantly higher in POMx compared with that in PLA at 48 h (85.4% +/- 2.5% and 78.3% +/- 2.6%, P = 0.01) and 72 h (88.9% +/- 2.0% and 84.0% +/- 2.0%, P = 0.009) after exercise. Serum markers of inflammation and muscle damage did not provide insight regarding possible mechanisms.
Supplementation with ellagitannins from pomegranate extract significantly improves recovery of isometric strength 2-3 d after a damaging eccentric exercise.
多酚，特别是鞣花单宁的饮食补充可能会减轻离心运动后经历的肌肉损伤，产生延迟性肌肉酸痛。本研究的目的是确定来自奇妙石榴提取物（POMx）的鞣花单宁补充剂是否改善了离心运动后骨骼肌力量的恢复。
将有娱乐性运动的男性随机分为交叉设计，分别给予石榴提取物（POMx）或安慰剂（PLA），每个周期为 9 天。为了产生延迟性肌肉酸痛，受试者用一只手臂进行两组 20 次最大离心肘部伸展运动。在运动后 2、24、48、72 和 96 小时测量最大等长肘部伸展力量和肌肉酸痛以及血清肌酸激酶、肌红蛋白、白细胞介素 6 和 C 反应蛋白。
在两种治疗中，运动后 2 小时力量相似下降（即基线的 72%），96 小时后力量恢复不完全（即基线的 91%）。然而，与 PLA 相比，POMx 在 48 小时（85.4% +/- 2.5%和 78.3% +/- 2.6%，P = 0.01）和 72 小时（88.9% +/- 2.0%和 84.0% +/- 2.0%，P = 0.009）时的力量更高。炎症和肌肉损伤的血清标志物没有提供可能的机制的见解。
石榴提取物中的鞣花单宁补充剂可显著改善损伤性离心运动后 2-3 天等长力量的恢复。
