Department of Cardiovascular Medicine, University of Tokyo Graduate School of Medicine, Tokyo, Japan.
Kidney Blood Press Res. 2009;32(6):421-7. doi: 10.1159/000264233. Epub 2009 Dec 3.
By analyzing data from 2,861 individuals who underwent general health screening 2 years running, we have investigated the impact of changes in waist circumference (WC) and body mass index (BMI) over a 1-year period on systolic blood pressure (BPs). We termed WC, BMI, and BPs at the first visit as WC1, BMI1, and BPs1, respectively, and those at the second visit as WC2, BMI2, and BPs2, respectively. The %dWC, %dBMI, and %dBPs was defined as (WC2 - WC1)/WC1 x 100, (BMI2 - BMI1)/BMI1 x 100, and (BPs2 - BPs1)/BPs1 x 100, respectively.
In multivariate regression analysis using age, BPs1, WC1, and %dWC as independent variables, %dWC was a significant predictor for %BPs only in men. %dBMI was a significant predictor for %BPs in both genders when age, BPs1, BMI1, and %dBMI were used as independent variables. Compared with individuals with both %dWC <0 and %dBMI <0, age-adjusted %dBPs was significantly greater in those with both %dWC <0 and %dBMI >or=0; however, it did not significantly differ in those with both %dWC >or=0 and %dBMI <0.
Our data suggest that the impact of BMI change might be greater than WC change in terms of BPs change during this short period.
通过分析连续两年接受一般健康检查的 2861 人的数据，我们研究了一年内腰围（WC）和体重指数（BMI）变化对收缩压（BPs）的影响。我们将第一次就诊时的 WC、BMI 和 BPs 分别称为 WC1、BMI1 和 BPs1，将第二次就诊时的 WC、BMI 和 BPs 分别称为 WC2、BMI2 和 BPs2。%dWC、%dBMI 和 %dBPs 定义为（WC2-WC1）/WC1 x 100、（BMI2-BMI1）/BMI1 x 100 和（BPs2-BPs1）/BPs1 x 100。
在使用年龄、BPs1、WC1 和 %dWC 作为自变量的多元回归分析中，%dWC 仅在男性中是 %BPs 的显著预测因子。当使用年龄、BPs1、BMI1 和 %dBMI 作为自变量时，%dBMI 是两性中 %BPs 的显著预测因子。与 %dWC<0 和 %dBMI<0 的个体相比，年龄校正后的 %dBPs 在 %dWC<0 和 %dBMI>=0 的个体中显著更高；然而，在 %dWC>=0 和 %dBMI<0 的个体中，它没有显著差异。
我们的数据表明，在短时间内，BMI 变化对 BPs 变化的影响可能大于 WC 变化。
