Department of Physiological Science, Brain Research Institute, University of California, Los Angeles, 90095, USA.
Exerc Sport Sci Rev. 2009 Oct;37(4):171-8. doi: 10.1097/JES.0b013e3181b7b932.
The lumbosacral spinal cord of mammals contains the neural circuitry capable of generating full weight-bearing locomotion of the hind limbs without any supraspinal input. One or more interventions, for example, pharmacological, epidural stimulation, and/or locomotor training, however, are necessary to gain access to and modulate the properties of this circuitry and to facilitate recovery of full weight-bearing locomotion after spinal cord injury.
哺乳动物的腰骶脊髓包含有生成无需任何上位神经输入的完整负重后肢运动的神经回路。然而,需要一种或多种干预措施,例如药理学、硬膜外刺激和/或运动训练,以获得对该回路的特性进行调节,并促进脊髓损伤后完全负重运动的恢复。