Health Information Department, Cancer Research UK, 61 Lincoln's Inn Fields, London, UK.
Br J Cancer. 2009 Dec 3;101 Suppl 2(Suppl 2):S68-72. doi: 10.1038/sj.bjc.6605394.
UK oral cancer incidence has risen by 22% in the last 10 years. Oral cancer is often detected at a late stage when treatment is debilitating and the chances of survival are poor. Certain black and minority ethnic groups are at elevated risk of oral cancer due to the prevalence of risk factor behaviours. We describe the background to, the development of and outcomes of an oral cancer screening activity appropriate to the needs of members of a disadvantaged community at high risk of oral cancer, carried out between 2006 and 2008 in Tower Hamlets, East London.
In all, 1320 people participated during 34 days of screening, divided into two phases (Phase I (2006/2007): n=485, Phase II (2008): n=835). Modifications to the delivery process were implemented for Phase II in an attempt to recruit more high-risk individuals and to improve screening specificity.
In total, 75 people were urgently referred for further investigation (Phase I: n=20, Phase II: n= 55). Nine were diagnosed with dysplastic lesions (Phase I: n=3, Phase II: n=6) and a further eight showed potentially malignant disorders without dysplasia (Phase I: n=1, Phase II: n=7). Screening participants with low levels of completed education (OR: 6.94, 95% CI: 1.66, 28.98) and who chewed paan with tobacco (OR: 8.01, 95% CI: 3.54, 18.08) were more likely to be referred for further investigation.
The project offers insights for the further development of oral cancer screening interventions for disadvantaged communities.
在过去的 10 年中，英国口腔癌的发病率上升了 22%。由于治疗效果不佳，且生存机会较差，口腔癌通常在晚期才被发现。某些黑人及少数族裔群体由于存在风险因素行为，因此口腔癌的风险较高。我们描述了 2006 年至 2008 年在东伦敦塔哈姆雷特（Tower Hamlets）开展的一项针对高危口腔癌的弱势社区成员的口腔癌筛查活动的背景、发展和结果。
在 34 天的筛查期间，共有 1320 人参加了筛查，分为两个阶段（第一阶段（2006/2007）：n=485；第二阶段（2008）：n=835）。第二阶段调整了服务提供过程，旨在招募更多高危人群并提高筛查的特异性。
共有 75 人被紧急转介进行进一步检查（第一阶段：n=20；第二阶段：n=55）。9 人被诊断为发育不良病变（第一阶段：n=3；第二阶段：n=6），另有 8 人表现出无发育不良的潜在恶性疾病（第一阶段：n=1；第二阶段：n=7）。受教育程度较低（OR：6.94，95%CI：1.66，28.98）和咀嚼含烟草的槟榔（OR：8.01，95%CI：3.54，18.08）的筛查参与者更有可能被转介进行进一步检查。
该项目为弱势社区口腔癌筛查干预措施的进一步发展提供了见解。
