弥散成像在脑肿瘤治疗反应评估中的应用。
Diffusion imaging for therapy response assessment of brain tumor.
机构信息
Department of Radiology, University of Michigan Medical Center, Ann Arbor, MI 48109, USA.
出版信息
Neuroimaging Clin N Am. 2009 Nov;19(4):559-71. doi: 10.1016/j.nic.2009.08.009.
Abstract
Advanced imaging provides insight into biophysical, physiologic, metabolic, or functional properties of tissues. Because water mobility is sensitive to cellular homeostasis, cellular density, and microstructural organization, it is considered a valuable tool in the advanced imaging arsenal. This article summarizes diffusion imaging concepts and highlights clinical applications of diffusion MR imaging for oncologic imaging. Diffusion tensor imaging and its derivative maps of diffusion anisotropy allow assessment of tumor compression or destruction of adjacent normal tissue anisotropy and may aid to assess tumor infiltration and aid presurgical planning.
摘要
高级成像是对组织的生物物理、生理、代谢或功能特性的深入了解。由于水的流动性对细胞内环境、细胞密度和微观结构组织敏感，因此它被认为是高级成像武器库中的一种有价值的工具。本文总结了扩散成像的概念，并强调了扩散磁共振成像在肿瘤成像中的临床应用。扩散张量成像及其扩散各向异性的衍生图可评估肿瘤对邻近正常组织各向异性的压迫或破坏，并且可能有助于评估肿瘤浸润程度并辅助术前规划。
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