恶性脑胶质瘤的治疗进展：现状与展望。

Therapeutic advances in malignant glioma: current status and future prospects.

机构信息

Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA.

出版信息

Neuroimaging Clin N Am. 2009 Nov;19(4):647-56. doi: 10.1016/j.nic.2009.08.015.

DOI:10.1016/j.nic.2009.08.015

PMID:19959010

Abstract

This article reviews the current status and trends in the treatment of primary gliomas, focusing predominantly on glioblastoma. It also discusses the current standard of care and new targeted agents currently under investigation. Furthermore, the concepts of pseudoprogression and pseudoresponse are introduced, which are new imaging correlates that have significant impact on understanding of the disease.

摘要

本文综述了原发性神经胶质瘤治疗的现状和趋势，主要关注胶质母细胞瘤。本文还讨论了目前的治疗标准和正在研究的新靶向药物。此外，还介绍了假性进展和假性缓解的概念，这些新的影像学相关性对理解疾病具有重要影响。