Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, UK.
Schizophr Bull. 2011 Jul;37(4):800-10. doi: 10.1093/schbul/sbp135. Epub 2009 Dec 3.
To undertake a systematic review and meta-analysis on the risk of repeat offending in individuals with psychosis and to assess the effect of potential moderating characteristics on risk estimates.
A systematic search was conducted in 6 bibliographic databases from January 1966 to January 2009, supplemented with correspondence with authors. Studies that reported risks of repeat offending in individuals with psychotic disorders (n = 3511) compared with individuals with other psychiatric disorders (n = 5446) and healthy individuals (n = 71 552) were included. Risks of repeat offending were calculated using fixed- and random-effects models to calculate pooled odds ratios (ORs). Subgroup and meta-regression analyses were conducted to examine how risk estimates were affected by various study characteristics including mean sample age, study location, sample size, study period, outcome measure, duration of follow-up, and diagnostic criteria.
Twenty-seven studies, which included 3511 individuals with psychosis, were identified. Compared with individuals without any psychiatric disorders, there was a significantly increased risk of repeat offending in individuals with psychosis (pooled OR = 1.6, 95% confidence interval [CI] = 1.4-1.8), although this was only based on 4 studies. In contrast, there was no association when individuals with other psychiatric disorders were used as the comparison group (pooled OR = 1.0, 95% CI = 0.7-1.3), although there was substantial heterogeneity. Higher risk estimates were found in female-only samples with psychosis and in studies conducted in the United States.
The association between psychosis and repeat offending differed depending on the comparison group. Despite this, we found no support for the findings of previous reviews that psychosis is associated with a lower risk of repeat offending.
对精神病患者再犯罪风险进行系统回顾和荟萃分析,并评估潜在调节特征对风险估计的影响。
从 1966 年 1 月至 2009 年 1 月,我们在 6 个文献数据库中进行了系统搜索,并与作者进行了通信。我们纳入了报告精神病障碍患者(n = 3511)与其他精神障碍患者(n = 5446)和健康个体(n = 71552)相比再犯罪风险的研究。使用固定效应和随机效应模型计算再犯罪风险,计算汇总优势比(OR)。进行亚组和荟萃回归分析,以检查风险估计如何受到各种研究特征的影响,包括平均样本年龄、研究地点、样本量、研究期间、结局测量、随访时间和诊断标准。
我们确定了 27 项研究,共纳入 3511 名精神病患者。与没有任何精神障碍的个体相比,精神病患者的再犯罪风险显著增加(汇总 OR = 1.6,95%置信区间 [CI] = 1.4-1.8),尽管这仅基于 4 项研究。相比之下,当使用其他精神障碍患者作为对照组时,没有关联(汇总 OR = 1.0,95% CI = 0.7-1.3),尽管存在很大的异质性。仅在女性精神病患者样本和美国进行的研究中发现风险估计值较高。
精神病与再犯罪之间的关联取决于对照组。尽管如此,我们并未发现支持以前综述结果的证据,即精神病与再犯罪风险降低有关。