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树枝状大分子作为药物递送载体：生物活性化合物与树枝状大分子的非共价相互作用。

Dendrimers as drug delivery vehicles: non-covalent interactions of bioactive compounds with dendrimers.

作者信息

Crampton Hannah L, Simanek Eric E

机构信息

Department of Chemistry, Texas A&M University, College Station, TX 77843-3255, USA.

出版信息

Polym Int. 2007 Mar 2;56(4):489-496. doi: 10.1002/pi.2230.

DOI:10.1002/pi.2230
PMID:19960104
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2786088/
Abstract

This mini review highlights issues associated with the use of dendrimers as drug delivery vehicles. The review introduces dendrimers and summarizes findings on their use in vivo and in vitro. Specifically, this review is limited to examples wherein the drug is non-covalently associated with the dendrimer. Examples wherein the drug is covalently attached to the dendrimer are not discussed.

摘要

本综述着重介绍了与树枝状大分子作为药物递送载体使用相关的问题。该综述介绍了树枝状大分子，并总结了其在体内和体外使用的研究结果。具体而言，本综述仅限于药物与树枝状大分子非共价结合的实例。药物与树枝状大分子共价连接的实例不在讨论范围内。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc1f/2786088/e1262cb16944/nihms157491f10.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc1f/2786088/e1262cb16944/nihms157491f10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc1f/2786088/61651e8af2e7/nihms157491f1.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc1f/2786088/0bc260c92deb/nihms157491f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc1f/2786088/7e4d328d5e5e/nihms157491f7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc1f/2786088/b0abb9e376f9/nihms157491f8.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc1f/2786088/e1262cb16944/nihms157491f10.jpg

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