Department of Chemistry, University of California, Berkeley, MC 1460 Berkeley, California 94720-1460, USA.
Org Lett. 2010 Jan 1;12(1):200-3. doi: 10.1021/ol902622b.
An enantioselective gold(I)-catalyzed intramolecular [4 + 2]-cycloaddition of allenes and dienes is reported. The reactions allow for the asymmetric synthesis of trans-hexahydroindenes and pyrrolidine products using C(3)-symmetric phosphitegold(I) and ortho-arylphosphoramiditegold(I) complexes as catalysts, respectively.
报道了一种对映选择性的金(I)催化的丙二烯和二烯的分子内[4 + 2]-环加成反应。该反应分别使用 C(3)-对称膦酸酯金(I)和邻-芳基磷酰胺基金(I)配合物作为催化剂,实现了反式六氢茚和吡咯烷产物的不对称合成。