Montero M Angeles, de Gracia Javier, Morell Ferràn
Hospital Universitario Vall d'Hebron, Barcelona, España.
Arch Bronconeumol. 2010 Sep;46(9):489-91. doi: 10.1016/j.arbres.2009.10.007. Epub 2009 Dec 4.
Hard metal lung disease is an unusual disease which can occur in individuals exposed to hard metals. Clinically, the condition resembles hypersensitivity pneumonitis depending mainly on individual susceptibility, which eventually progresses to pulmonary fibrosis. We present two patients with pulmonary fibrosis, who were actually diagnosed after an exhaustive anamnesis and examination of the tissue by scanning microscope to discard hard metals. The evaluation of wedge biopsies by scanning electronic microscope can be very helpful in those cases without a specific diagnosis.
硬金属肺病是一种罕见疾病,可发生于接触硬金属的个体。临床上,该病类似于超敏性肺炎,主要取决于个体易感性,最终会发展为肺纤维化。我们报告了两名肺纤维化患者,他们实际上是在经过详尽的问诊和扫描显微镜检查组织以排除硬金属后才得以确诊。对于那些没有明确诊断的病例,通过扫描电子显微镜对楔形活检组织进行评估可能会非常有帮助。