Gibbs-Strauss Summer L, Rosenberg Mireille, Clough Barbara L, Troyan Susan L, Frangioni John V
Department of Radiology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Room SL-B05, Boston, MA 02215, USA.
Annu Int Conf IEEE Eng Med Biol Soc. 2009;2009:2001-4. doi: 10.1109/IEMBS.2009.5333429.
Clinical translation of scientific discoveries is often the long-term goal of academic medical research. However, this goal is not always realized due to the complicated path between bench research and clinical use. In this review, we outline the fundamental steps required for first-in-human testing of a new imaging device, and use the FLARE() (Fluorescence-Assisted Resection and Exploration) near-infrared fluorescence optical imaging platform as an example.
科学发现的临床转化往往是学术医学研究的长期目标。然而，由于基础研究与临床应用之间的路径复杂，这一目标并非总能实现。在本综述中，我们概述了新型成像设备首次人体试验所需的基本步骤，并以FLARE（荧光辅助切除与探查）近红外荧光光学成像平台为例进行说明。
