Ballard John R, Casper Andrew J, Ebbini Emad S
Department of Electrical and Computer Engineering, University of Minnesota Twin Cities, USA.
Annu Int Conf IEEE Eng Med Biol Soc. 2009;2009:137-40. doi: 10.1109/IEMBS.2009.5334677.
We present experimental results illustrating the unique advantages of dual-mode array (DMUA) systems in monitoring and guidance of high intensity focused ultrasound (HIFU) lesion formation. DMUAs offer a unique paradigm in image-guided surgery; one in which images obtained using the same therapeutic transducer provide feedback for: 1) refocusing the array in the presence of strongly scattering objects, e.g. the ribs, 2) temperature change at the intended location of the HIFU focus, and 3) changes in the echogenicity of the tissue in response to therapeutic HIFU. These forms of feedback have been demonstrated in vitro in preparation for the design and implementation of a real-time system for imaging and therapy with DMUAs. The results clearly demonstrate that DMUA image feedback is spatially accurate and provide sufficient spatial and contrast resolution for identification of high contrast objects like the ribs and significant blood vessels in the path of the HIFU beam.
我们展示了实验结果，这些结果说明了双模阵列（DMUA）系统在高强度聚焦超声（HIFU）损伤形成的监测和引导方面的独特优势。DMUAs在图像引导手术中提供了一种独特的范例；在这种范例中，使用同一治疗换能器获得的图像可为以下方面提供反馈：1）在存在强散射物体（如肋骨）的情况下重新聚焦阵列，2）HIFU焦点预期位置的温度变化，以及3）组织回声性因治疗性HIFU而发生的变化。这些反馈形式已在体外得到证实，为设计和实施用于DMUAs成像与治疗的实时系统做准备。结果清楚地表明，DMUA图像反馈在空间上是准确的，并且为识别HIFU束路径中的高对比度物体（如肋骨和重要血管）提供了足够的空间和对比度分辨率。
