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评估法国老年病房医护人员流感疫苗接种计划:一项整群随机对照试验。

Assessment of healthcare worker influenza vaccination program in French geriatric wards: a cluster-randomized controlled trial.

机构信息

ORIG, Charles Foix Hospital, Ivry sur Seine, France.

出版信息

Aging Clin Exp Res. 2010 Oct-Dec;22(5-6):450-5. doi: 10.1007/BF03337740. Epub 2009 Nov 27.

Abstract

BACKGROUND AND AIMS

The French institute for study of geriatric infection risk (ORIG) has run a multiphase multicenter study (VESTA) to develop and implement active programs promoting healthcare worker (HCW) influenza vaccination. The present article reports results after implementation of the first active program.

METHOD

A cluster-randomized controlled trial was conducted from December 1 to December 15, 2005, and a total of 43 geriatric wards (3646 HCWs) were randomly assigned to two clusters. The program cluster (24 wards; 1918 HCWs) received the active program whereas no action was taken in the control cluster (19 wards; 1728 HCWs). The program was educational; its objective was to convince HCWs to be vaccinated by giving them topdown scientific information and developing a sense of altruism. Data from 1201 HCWs (63%) from the program cluster and 1144 HCWs (66%) from the control cluster were collected.

RESULTS

The program failed to increase the HCW influenza vaccination rate (program: 34%; control: 32%; p>0.05), but won the faithfulness of vaccinated HCWs (5% vs 8% HCWs quitted vaccination; p<0.05).

CONCLUSIONS

Resistance to active influenza vaccination programs was found. Future active programs will have to restore a climate of confidence between sources of knowledge and HCWs and promote "self-protection" in contrast with the protection of elderly people.

摘要

背景与目的

法国老年感染风险研究学会(ORIG)开展了一项多阶段多中心研究(VESTA),以制定并实施主动计划来促进医护人员(HCW)接种流感疫苗。本文报道了首次主动计划实施后的结果。

方法

一项集群随机对照试验于 2005 年 12 月 1 日至 12 月 15 日进行,共有 43 个老年病房(3646 名 HCW)被随机分为两组。该方案组(24 个病房;1918 名 HCW)接受了主动方案,而对照组(19 个病房;1728 名 HCW)则没有采取任何行动。该方案是教育性的,其目的是通过向 HCW 提供自上而下的科学信息并培养利他主义意识来说服他们接种疫苗。方案组收集了 1201 名(63%)和对照组 1144 名(66%)HCW 的数据。

结果

该方案未能提高 HCW 流感疫苗接种率(方案组:34%;对照组:32%;p>0.05),但赢得了已接种 HCW 的信任(5%的 HCW 退出接种;而对照组为 8%;p<0.05)。

结论

发现对主动流感疫苗接种计划存在抵制。未来的主动计划将不得不恢复知识来源和 HCW 之间的信任氛围,并促进“自我保护”,而不是保护老年人。

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