Department of Surgical Oncology and Technology, St. Mary's National Health Service Trust, London, United Kingdom.
Dis Colon Rectum. 2009 Oct;52(10):1695-704. doi: 10.1007/DCR.0b013e3181b55254.
This study was designed to compare outcomes after elective laparoscopic and conventional colorectal surgery over a ten-year period using data from the English National Health Service Hospital Episode Statistics database.
All elective colonic and rectal resections carried out in English Trusts between 1996 and 2006 were included. Univariate and multivariate analyses were used to compare 30 and 365-day mortality rates, 28-day readmission rates, and length of stay between laparoscopic and open surgery.
Between the study dates 3,709 of 192,620 (1.9%) elective colonic and rectal resections were classified as laparoscopically assisted procedures. The 30-day and 365-day mortality rates were lower after laparoscopic resection than after open surgery (P < 0.05). After correction for age, gender, diagnosis, operation type, comorbidity, and social deprivation, laparoscopic surgery was a strong determinant of reduced 30-day (odds ratio, 0.57; 95% confidence interval, 0.44-0.74; P < 0.001) and one-year (odds ratio, 0.53; 95% confidence interval, 0.42-0.67; P < 0.001) mortality. Similarly, multivariate analysis confirmed that laparoscopic surgery was independently associated with reduced hospital stay (P < 0.001). Patients who received rectal procedures for malignancy, however, were more likely to be readmitted if laparoscopy rather than by a traditional method was used (11.9% vs. 9.1%, P = 0.003).
In the present study, patients selected for laparoscopic colorectal surgery were associated with reduced postoperative mortality when compared with those undergoing the conventional technique. This finding merits further investigation.
本研究旨在利用英国国家卫生服务医院病例统计数据库的数据,比较 10 年间择期腹腔镜与传统结直肠手术的结果。
纳入 1996 年至 2006 年期间在英国信托基金中进行的所有择期结肠和直肠切除术。使用单变量和多变量分析比较腹腔镜和开放手术 30 天和 365 天死亡率、28 天再入院率和住院时间。
在研究期间,192620 例择期结肠和直肠切除术中有 3709 例(1.9%)被归类为腹腔镜辅助手术。腹腔镜切除术后 30 天和 365 天的死亡率低于开放手术(P < 0.05)。在纠正年龄、性别、诊断、手术类型、合并症和社会贫困后,腹腔镜手术是降低 30 天(比值比,0.57;95%置信区间,0.44-0.74;P < 0.001)和 1 年(比值比,0.53;95%置信区间,0.42-0.67;P < 0.001)死亡率的重要因素。同样,多变量分析证实腹腔镜手术与缩短住院时间独立相关(P < 0.001)。然而,对于接受恶性直肠手术的患者,如果使用腹腔镜而不是传统方法,其再入院的可能性更高(11.9%比 9.1%,P = 0.003)。
在本研究中,与接受传统技术的患者相比,接受腹腔镜结直肠手术的患者术后死亡率降低。这一发现值得进一步研究。