Méan M, Aujesky D
Service de médecine interne, CHUV, 1011 Lausanne.
Rev Med Suisse. 2009 Oct 28;5(223):2142-4, 2146.
Venous thromboembolism (VTE) is a common disease and has a high impact on morbidity, mortality, and costs of care. The majority of patients with VTE are aged > or = 65 years, making VTE essentially a disease of the elderly. Despite its high prevalence and the fact that VTE has a less favourable outcome in elderly patients (e.g., higher rate of mortality, major bleeding, and post-thrombotic syndrome), older patients are underrepresented in prospective studies of VTE. Moreover, little is known about patient factors that determine medical outcomes, quality of life, and costs of care in elderly patients with VTE. The goal of this article is to review the existing evidence regarding VTE in the elderly. A prospective multicenter Swiss cohort study will examine medical outcomes, quality of life, and medical resource utilization in elderly patients with VTE.
静脉血栓栓塞症(VTE)是一种常见疾病,对发病率、死亡率和护理成本有很大影响。大多数VTE患者年龄≥65岁,这使得VTE基本上成为一种老年疾病。尽管VTE患病率很高,且老年患者的VTE预后较差(例如,死亡率、大出血和血栓形成后综合征的发生率较高),但在VTE的前瞻性研究中,老年患者的代表性不足。此外,对于决定老年VTE患者医疗结局、生活质量和护理成本的患者因素知之甚少。本文的目的是综述关于老年VTE的现有证据。一项前瞻性多中心瑞士队列研究将考察老年VTE患者的医疗结局、生活质量和医疗资源利用情况。