两种新的异贝壳杉烷二萜类化合物来自于鼯鼠科粪便。
Two new isopimarane diterpenes from the feces of Trogopterus xanthipes.
机构信息
Jiangsu Key Laboratory for TCM Formulae Research, Nanjing University of Traditional Chinese Medicine, Nanjing, China.
出版信息
Fitoterapia. 2010 Jul;81(5):381-4. doi: 10.1016/j.fitote.2009.11.006. Epub 2009 Nov 30.
PMID:19954761
Abstract
Chemical investigation of Trogopterus Feces has led to the isolation of two new isopimarane diterpenes, wulingzhic acid A (1) and wulingzhic acid B (2). Their structures were elucidated by chemical and extensive spectral analysis. Compounds 1 and 2 exhibited weak activity of antithrombin and moderate activity of antiplatelet aggregation in vitro.
摘要
对五灵脂的化学成分进行研究，从中分离得到两个新的松脂烷二萜化合物，五灵脂酸 A（1）和五灵脂酸 B（2）。通过化学和广泛的光谱分析确定了它们的结构。化合物 1 和 2 在体外显示出微弱的抗凝血酶活性和适度的抗血小板聚集活性。
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