Department of Neurosurgery, National Hospital Organization Disaster Medical Center, 3256 Midori-cho, Tachikawa-shi, Tokyo 190-0014, Japan.
J Clin Neurosci. 2010 Jan;17(1):153-4. doi: 10.1016/j.jocn.2009.03.043. Epub 2009 Dec 9.
Epstein-Barr virus (EBV) encephalitis is a rare neurological complication, usually only reported in pediatric patients. We present a 20-year-old, previously healthy male who developed hemorrhagic encephalitis caused by EBV. He was admitted to our hospital with a 1-week history of fever, diarrhea, headache, and confusion. Brain T2-weighted MRI showed a focal area of increased signal in the right temporal lobe. Brain MRI and CT scans on day 2 revealed progression of the lesion, with partial hemorrhagic change, acute brain swelling, and severe midline shift. The patient underwent external decompression and external ventricular drainage. EBV DNA was identified in brain biopsy specimens by polymerase chain reaction. The postoperative course was uneventful. To our knowledge, this is the second report of hemorrhagic EBV encephalitis in an adult.
爱泼斯坦-巴尔病毒（EBV）脑炎是一种罕见的神经系统并发症，通常仅在儿科患者中报告。我们报告了一例 20 岁的既往健康男性，他因 EBV 引起出血性脑炎。他因发热、腹泻、头痛和意识混乱入院，病史 1 周。脑 T2 加权 MRI 显示右侧颞叶有局灶性信号增强区。入院第 2 天的脑 MRI 和 CT 扫描显示病变进展，伴有部分出血性改变、急性脑肿胀和严重中线移位。患者接受了外减压和外部脑室引流。聚合酶链反应在脑活检标本中鉴定出 EBV DNA。术后过程顺利。据我们所知，这是成人出血性 EBV 脑炎的第二例报告。
