Exploring innate glycopeptide resistance mechanisms in Staphylococcus aureus.
作者信息
Renzoni Adriana, Kelley William L, Vaudaux Pierre, Cheung Ambrose L, Lew Daniel P
机构信息
Service of Infectious Diseases, Geneva University Hospital, CH-1211 Geneva 14, Switzerland.
出版信息
Trends Microbiol. 2010 Feb;18(2):55-6. doi: 10.1016/j.tim.2009.11.005. Epub 2009 Dec 11.
Abstract
摘要
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Identification by genomic and genetic analysis of two new genes playing a key role in intermediate glycopeptide resistance in Staphylococcus aureus.通过基因组和遗传分析鉴定出在金黄色葡萄球菌对中间糖肽耐药性中起关键作用的两个新基因。
Antimicrob Agents Chemother. 2009 Mar;53(3):903-11. doi: 10.1128/AAC.01287-08. Epub 2008 Dec 22.
2
Genomic analysis reveals a point mutation in the two-component sensor gene graS that leads to intermediate vancomycin resistance in clinical Staphylococcus aureus.基因组分析揭示了双组分传感器基因graS中的一个点突变，该突变导致临床金黄色葡萄球菌对万古霉素产生中度耐药性。
Antimicrob Agents Chemother. 2008 Oct;52(10):3755-62. doi: 10.1128/AAC.01613-07. Epub 2008 Jul 21.
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Tracking the in vivo evolution of multidrug resistance in Staphylococcus aureus by whole-genome sequencing.通过全基因组测序追踪金黄色葡萄球菌中多药耐药性的体内进化
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Interaction of the GraRS two-component system with the VraFG ABC transporter to support vancomycin-intermediate resistance in Staphylococcus aureus.GraRS双组分系统与VraFG ABC转运蛋白的相互作用以支持金黄色葡萄球菌的万古霉素中介耐药性。
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Overexpression of genes of the cell wall stimulon in clinical isolates of Staphylococcus aureus exhibiting vancomycin-intermediate- S. aureus-type resistance to vancomycin.在表现出万古霉素中介金黄色葡萄球菌型万古霉素耐药性的金黄色葡萄球菌临床分离株中细胞壁刺激子基因的过表达。
J Bacteriol. 2006 Feb;188(3):1120-33. doi: 10.1128/JB.188.3.1120-1133.2006.
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DNA microarray-based identification of genes associated with glycopeptide resistance in Staphylococcus aureus.基于DNA微阵列技术鉴定金黄色葡萄球菌中与糖肽耐药相关的基因。
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