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Exploring innate glycopeptide resistance mechanisms in Staphylococcus aureus.探索金黄色葡萄球菌中固有的糖肽抗性机制。
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Glycopeptide resistance in Staphylococcus aureus.金黄色葡萄球菌中的糖肽类耐药性。
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Antibiotic resistance in Staphylococcus aureus and its relevance in therapy.金黄色葡萄球菌中的抗生素耐药性及其在治疗中的相关性。
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The problem with glycopeptides.
Int J Antimicrob Agents. 2007 Jul;30(1):1-3. doi: 10.1016/j.ijantimicag.2007.03.006. Epub 2007 May 15.
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Glycopeptides--important treatment option for methicillin-resistant Staphylococcus aureus.糖肽类药物——耐甲氧西林金黄色葡萄球菌的重要治疗选择。
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Bactericidal activity of oxacillin and glycopeptides against Staphylococcus aureus in patients with endocarditis: looking for a relationship between tolerance and outcome.苯唑西林和糖肽类药物对感染性心内膜炎患者金黄色葡萄球菌的杀菌活性：寻找耐药性与结局的关系。
Ann Clin Microbiol Antimicrob. 2011 Jun 9;10:26. doi: 10.1186/1476-0711-10-26.
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Monitoring of vancomycin serum levels for the treatment of staphylococcal infections.监测万古霉素血清水平以治疗葡萄球菌感染。
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Methicillin-Resistant (MRSA): Resistance, Prevalence, and Coping Strategies.耐甲氧西林（MRSA）：耐药性、流行情况及应对策略。
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Staphylococcus aureus with reduced susceptibility to vancomycin in healthcare settings.在医疗机构中对万古霉素敏感性降低的金黄色葡萄球菌。
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Prevalence of isolates with reduced glycopeptide susceptibility in orthopedic device-related infections due to methicillin-resistant Staphylococcus aureus.耐甲氧西林金黄色葡萄球菌所致骨科器械相关感染中具有降低糖肽类药物敏感性的分离株的流行率。
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The posttranslocational chaperone lipoprotein PrsA is involved in both glycopeptide and oxacillin resistance in Staphylococcus aureus.转位后伴侣脂蛋白 PrsA 参与金黄色葡萄球菌的糖肽类和耐甲氧西林的抗性。
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High prevalence of isolates with reduced glycopeptide susceptibility in persistent or recurrent bloodstream infections due to methicillin-resistant Staphylococcus aureus.耐甲氧西林金黄色葡萄球菌引起的持续性或复发性血流感染中，具有降低糖肽类药物敏感性的分离株的高发生率。
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Site-specific mutation of Staphylococcus aureus VraS reveals a crucial role for the VraR-VraS sensor in the emergence of glycopeptide resistance.金黄色葡萄球菌 VraS 的位点特异性突变揭示了 VraR-VraS 传感器在糖肽类药物耐药性出现中的关键作用。
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Underestimation of vancomycin and teicoplanin MICs by broth microdilution leads to underdetection of glycopeptide-intermediate isolates of Staphylococcus aureus.肉汤微量稀释法低估万古霉素和替考拉宁 MIC 值会导致金黄色葡萄球菌糖肽中介体分离株漏检。
Antimicrob Agents Chemother. 2010 Sep;54(9):3861-70. doi: 10.1128/AAC.00269-10. Epub 2010 Jun 14.

本文引用的文献

1
Identification by genomic and genetic analysis of two new genes playing a key role in intermediate glycopeptide resistance in Staphylococcus aureus.通过基因组和遗传分析鉴定出在金黄色葡萄球菌对中间糖肽耐药性中起关键作用的两个新基因。
Antimicrob Agents Chemother. 2009 Mar;53(3):903-11. doi: 10.1128/AAC.01287-08. Epub 2008 Dec 22.
2
Genomic analysis reveals a point mutation in the two-component sensor gene graS that leads to intermediate vancomycin resistance in clinical Staphylococcus aureus.基因组分析揭示了双组分传感器基因graS中的一个点突变，该突变导致临床金黄色葡萄球菌对万古霉素产生中度耐药性。
Antimicrob Agents Chemother. 2008 Oct;52(10):3755-62. doi: 10.1128/AAC.01613-07. Epub 2008 Jul 21.
3
Molecular basis of resistance to muramidase and cationic antimicrobial peptide activity of lysozyme in staphylococci.葡萄球菌中溶菌酶对溶菌酶和阳离子抗菌肽活性产生抗性的分子基础。
PLoS Pathog. 2007 Jul 27;3(7):e102. doi: 10.1371/journal.ppat.0030102.
4
Tracking the in vivo evolution of multidrug resistance in Staphylococcus aureus by whole-genome sequencing.通过全基因组测序追踪金黄色葡萄球菌中多药耐药性的体内进化
Proc Natl Acad Sci U S A. 2007 May 29;104(22):9451-6. doi: 10.1073/pnas.0609839104. Epub 2007 May 21.
5
Interaction of the GraRS two-component system with the VraFG ABC transporter to support vancomycin-intermediate resistance in Staphylococcus aureus.GraRS双组分系统与VraFG ABC转运蛋白的相互作用以支持金黄色葡萄球菌的万古霉素中介耐药性。
Antimicrob Agents Chemother. 2007 Aug;51(8):2679-89. doi: 10.1128/AAC.00209-07. Epub 2007 May 14.
6
The rationale for revising the Clinical and Laboratory Standards Institute vancomycin minimal inhibitory concentration interpretive criteria for Staphylococcus aureus.修订临床和实验室标准协会金黄色葡萄球菌万古霉素最低抑菌浓度解释标准的基本原理。
Clin Infect Dis. 2007 May 1;44(9):1208-15. doi: 10.1086/513203. Epub 2007 Mar 28.
7
Strain dependence of the cell wall-damage induced stimulon in Staphylococcus aureus.金黄色葡萄球菌中细胞壁损伤诱导刺激子的菌株依赖性
Biochim Biophys Acta. 2006 Oct;1760(10):1475-81. doi: 10.1016/j.bbagen.2006.06.008. Epub 2006 Jul 1.
8
Correlation between Reduced Daptomycin Susceptibility and Vancomycin Resistance in Vancomycin-Intermediate Staphylococcus aureus.万古霉素中度敏感金黄色葡萄球菌中达托霉素敏感性降低与万古霉素耐药性之间的相关性
Antimicrob Agents Chemother. 2006 Mar;50(3):1079-82. doi: 10.1128/AAC.50.3.1079-1082.2006.
9
Overexpression of genes of the cell wall stimulon in clinical isolates of Staphylococcus aureus exhibiting vancomycin-intermediate- S. aureus-type resistance to vancomycin.在表现出万古霉素中介金黄色葡萄球菌型万古霉素耐药性的金黄色葡萄球菌临床分离株中细胞壁刺激子基因的过表达。
J Bacteriol. 2006 Feb;188(3):1120-33. doi: 10.1128/JB.188.3.1120-1133.2006.
10
DNA microarray-based identification of genes associated with glycopeptide resistance in Staphylococcus aureus.基于DNA微阵列技术鉴定金黄色葡萄球菌中与糖肽耐药相关的基因。
Antimicrob Agents Chemother. 2005 Aug;49(8):3404-13. doi: 10.1128/AAC.49.8.3404-3413.2005.

Exploring innate glycopeptide resistance mechanisms in Staphylococcus aureus.

作者信息

Renzoni Adriana, Kelley William L, Vaudaux Pierre, Cheung Ambrose L, Lew Daniel P

机构信息

Service of Infectious Diseases, Geneva University Hospital, CH-1211 Geneva 14, Switzerland.

出版信息

Trends Microbiol. 2010 Feb;18(2):55-6. doi: 10.1016/j.tim.2009.11.005. Epub 2009 Dec 11.

DOI:10.1016/j.tim.2009.11.005
PMID:20005114
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2847831/
Abstract
摘要