Section of Molecular Gastroenterology, Department of Internal Medicine I, University of Tuebingen, Tuebingen, Germany.
J Mol Cell Biol. 2010 Apr;2(2):78-80. doi: 10.1093/jmcb/mjp045. Epub 2009 Dec 11.
Dying cells actively attract professional phagocytes by sending out soluble 'find-me' signals. The characterization and identification of the corresponding molecular entities have revealed that 'find-me' signals come in different flavors, including peptides, proteins, lipids and complex structures, such as apoptotic microblebs. With the very recent report by Elliott et al., nucleotides as a novel nuance enter the menu.
垂死的细胞通过发出可溶性的“找我”信号主动吸引专业的吞噬细胞。这些相应分子实体的特征描述和鉴定表明，“找我”信号有不同的形式，包括肽、蛋白质、脂类和复杂结构，如凋亡小体。随着 Elliott 等人的最新报告，核苷酸作为一种新的细微差别进入了这个菜单。
