Gravante Gianpiero, Sorge Roberto, Merone Antonio, Tamisani Anna Maria, Di Lonardo Antonio, Scalise Alessandro, Doneddu Giovanna, Melandri Davide, Stracuzzi Giorgio, Onesti Maria Giuseppina, Cerulli Paolo, Pinn Raimondo, Esposito Gaetano
Department of Hepatobiliary and Pancreatic Surgery, University Hospitals of Leicester, Leicester, UK.
Ann Plast Surg. 2010 Jan;64(1):69-79. doi: 10.1097/SAP.0b013e31819b3d59.
Results of a national retrospective survey on Hyalomatrix PA in burn patients are reported.A total of 11 burn centers were contacted.A total of 57 patients were available. Hyalomatrix PA was used on young and adult patients, mainly in deep partial thickness and full thickness burns. In most cases, Hyalomatrix PA was applied immediately after the wound cleaning (wound debridement or escharectomy for adults, dermabrasion or debridement in young patients). After 7 days, reepithelization processes were more frequent in deep partial thickness burns. One-half of the patient population underwent grafting. After 29 days, complete closure was achieved in almost all patients. The Vancouver Scar Scale showed better values for adults, while no differences were observed for burn depth or patients undergoing grafting. No adverse reactions were recorded.Hyalomatrix PA is used in young and adults, in deep partial thickness and full thickness burns, as a temporary coverage before grafting or alone for wound healing.
本文报告了一项关于透明质酸基质PA(Hyalomatrix PA)在烧伤患者中的全国性回顾性调查结果。共联系了11个烧伤中心,共有57例患者可供研究。透明质酸基质PA应用于年轻及成年患者,主要用于深Ⅱ度和Ⅲ度烧伤。在大多数情况下,透明质酸基质PA在伤口清洁后立即应用(成年患者进行伤口清创或焦痂切除,年轻患者进行磨皮或清创)。7天后,深Ⅱ度烧伤创面的再上皮化过程更为频繁。一半的患者接受了植皮手术。29天后,几乎所有患者的创面均实现完全闭合。温哥华瘢痕量表显示成年患者的结果更好,而在烧伤深度或接受植皮手术的患者中未观察到差异。未记录到不良反应。透明质酸基质PA用于年轻及成年患者的深Ⅱ度和Ⅲ度烧伤,作为植皮前的临时覆盖物或单独用于伤口愈合。