Turner M A, Devlin J, David T J
Department of Child Health, University of Manchester.
Arch Dis Child. 1991 Feb;66(2):212-5. doi: 10.1136/adc.66.2.212.
Information was collected by telephone about 300 holidays taken over a three year period by 126 children with severe atopic eczema. During the holidays, improvement in eczema occurred more frequently (112/300, 37%) than deterioration (63/300, 21%). There was a significant correlation between improvement and a more southerly holiday location: improvement was common in holidays taken in the Mediterranean or further south (63/92, 69%), but holidays in northern Britain were more likely to be associated with deterioration (27/100, 27%) than improvement (13/100, 13%). Changes in eczema were correlated with changes in asthma in 231 holidays taken by children with both conditions, but improvement was not significantly associated with pet ownership. All patients returned to their preholiday state, usually within two weeks of return home. The causes of changes in eczema while on holiday have not been identified.
通过电话收集了126名重度特应性湿疹患儿在三年期间度过的300个假期的相关信息。在假期中，湿疹改善的情况比恶化更为常见（112/300，37%），恶化的情况占（63/300，21%）。湿疹改善与更靠南的度假地点之间存在显著相关性：在地中海地区或更南部度假时湿疹改善很常见（63/92，69%），但在英国北部度假时，与恶化（27/100，27%）相比，改善的可能性更小（13/100，13%）。在患有这两种疾病的患儿度过的231个假期中，湿疹变化与哮喘变化相关，但改善与是否拥有宠物没有显著关联。所有患者通常在回家后两周内恢复到度假前的状态。度假期间湿疹变化的原因尚未明确。
