单细胞模式生物中复制程序的分子分析。
Molecular analysis of the replication program in unicellular model organisms.
机构信息
Department of Genome Sciences, University of Washington, Box 355065, Seattle, WA, 98133, USA.
出版信息
Chromosome Res. 2010 Jan;18(1):19-34. doi: 10.1007/s10577-009-9099-x.
Abstract
Eukaryotes have long been reported to show temporal programs of replication, different portions of the genome being replicated at different times in S phase, with the added possibility of developmentally regulated changes in this pattern depending on species and cell type. Unicellular model organisms, primarily the budding yeast Saccharomyces cerevisiae, have been central to our current understanding of the mechanisms underlying the regulation of replication origins and the temporal program of replication in particular. But what exactly is a temporal program of replication, and how might it arise? In this article, we explore this question, drawing again on the wealth of experimental information in unicellular model organisms.
摘要
真核生物长期以来一直被报道显示出时间复制程序，基因组的不同部分在 S 期的不同时间复制，并且根据物种和细胞类型，这种模式可能会有发育调节的变化。单细胞模式生物，主要是芽殖酵母酿酒酵母，是我们当前理解复制起点调控和复制时间程序的基础。但是，什么是复制的时间程序，它是如何产生的呢？在本文中，我们再次利用单细胞模式生物丰富的实验信息来探讨这个问题。
相似文献
1
Molecular analysis of the replication program in unicellular model organisms.
Chromosome Res. 2010 Jan;18(1):19-34. doi: 10.1007/s10577-009-9099-x.
2
Replication dynamics of the yeast genome.
Science. 2001 Oct 5;294(5540):115-21. doi: 10.1126/science.294.5540.115.
3
A model for the spatiotemporal organization of DNA replication in Saccharomyces cerevisiae.
Mol Genet Genomics. 2009 Jul;282(1):25-35. doi: 10.1007/s00438-009-0443-9. Epub 2009 Mar 22.
4
CLB5-dependent activation of late replication origins in S. cerevisiae.
Mol Cell. 1998 Aug;2(2):173-82. doi: 10.1016/s1097-2765(00)80127-6.
5
Different nucleosomal architectures at early and late replicating origins in Saccharomyces cerevisiae.
BMC Genomics. 2014 Sep 13;15(1):791. doi: 10.1186/1471-2164-15-791.
6
Different groups of metabolic genes cluster around early and late firing origins of replication in budding yeast.
Genome Inform. 2010;24:179-92.
7
Analyzing origin activation patterns by copy number change experiments.
Methods Mol Biol. 2009;521:279-94. doi: 10.1007/978-1-60327-815-7_15.
8
The dynamics of chromosome replication in yeast.
Curr Top Dev Biol. 2003;55:1-73. doi: 10.1016/s0070-2153(03)01001-9.
9
The temporal program of chromosome replication: genomewide replication in clb5{Delta} Saccharomyces cerevisiae.
Genetics. 2008 Dec;180(4):1833-47. doi: 10.1534/genetics.108.094359. Epub 2008 Oct 1.
10
Live-cell imaging reveals replication of individual replicons in eukaryotic replication factories.
Cell. 2006 Jun 30;125(7):1297-308. doi: 10.1016/j.cell.2006.04.041.
引用本文的文献
1
The yeast Dbf4 Zn finger domain suppresses single-stranded DNA at replication forks initiated from a subset of origins.
Curr Genet. 2022 Apr;68(2):253-265. doi: 10.1007/s00294-022-01230-6. Epub 2022 Feb 11.
2
Genomic methods for measuring DNA replication dynamics.
Chromosome Res. 2020 Mar;28(1):49-67. doi: 10.1007/s10577-019-09624-y. Epub 2019 Dec 17.
3
On the Interplay of the DNA Replication Program and the Intra-S Phase Checkpoint Pathway.
Genes (Basel). 2019 Jan 29;10(2):94. doi: 10.3390/genes10020094.
4
How MCM loading and spreading specify eukaryotic DNA replication initiation sites.
F1000Res. 2016 Aug 24;5. doi: 10.12688/f1000research.9008.1. eCollection 2016.
5
The Eukaryotic Mismatch Recognition Complexes Track with the Replisome during DNA Synthesis.
PLoS Genet. 2015 Dec 18;11(12):e1005719. doi: 10.1371/journal.pgen.1005719. eCollection 2015 Dec.
6
Chromosomal context and replication properties of ARS plasmids in Schizosaccharomyces pombe.
J Biosci. 2015 Dec;40(5):845-53. doi: 10.1007/s12038-015-9572-y.
7
Genome architecture and its roles in human copy number variation.
Genomics Inform. 2014 Dec;12(4):136-44. doi: 10.5808/GI.2014.12.4.136. Epub 2014 Dec 31.
8
Peaks cloaked in the mist: the landscape of mammalian replication origins.
J Cell Biol. 2015 Jan 19;208(2):147-60. doi: 10.1083/jcb.201407004.
9
Checkpoint-independent scaling of the Saccharomyces cerevisiae DNA replication program.
BMC Biol. 2014 Oct 7;12:79. doi: 10.1186/s12915-014-0079-z.
10
High-resolution replication profiles define the stochastic nature of genome replication initiation and termination.
Cell Rep. 2013 Nov 27;5(4):1132-41. doi: 10.1016/j.celrep.2013.10.014. Epub 2013 Nov 7.
本文引用的文献
1
Fragile genomic sites are associated with origins of replication.
Genome Biol Evol. 2009 Sep 9;1:350-63. doi: 10.1093/gbe/evp034.
2
Centromere replication timing determines different forms of genomic instability in Saccharomyces cerevisiae checkpoint mutants during replication stress.
Genetics. 2009 Dec;183(4):1249-60. doi: 10.1534/genetics.109.107508. Epub 2009 Oct 5.
3
Predictable dynamic program of timing of DNA replication in human cells.
Genome Res. 2009 Dec;19(12):2288-99. doi: 10.1101/gr.094060.109. Epub 2009 Sep 18.
4
Computational methods to study kinetics of DNA replication.
Methods Mol Biol. 2009;521:555-73. doi: 10.1007/978-1-60327-815-7_32.
5
Universal temporal profile of replication origin activation in eukaryotes.
PLoS One. 2009 Jun 12;4(6):e5899. doi: 10.1371/journal.pone.0005899.
6
Additions, losses, and rearrangements on the evolutionary route from a reconstructed ancestor to the modern Saccharomyces cerevisiae genome.
PLoS Genet. 2009 May;5(5):e1000485. doi: 10.1371/journal.pgen.1000485. Epub 2009 May 15.
7
Genome-wide replication profiles indicate an expansive role for Rpd3L in regulating replication initiation timing or efficiency, and reveal genomic loci of Rpd3 function in Saccharomyces cerevisiae.
Genes Dev. 2009 May 1;23(9):1077-90. doi: 10.1101/gad.1784309.
8
Replication timing and transcriptional control: beyond cause and effect--part II.
Curr Opin Genet Dev. 2009 Apr;19(2):142-9. doi: 10.1016/j.gde.2009.02.002. Epub 2009 Apr 1.
9
A model for the spatiotemporal organization of DNA replication in Saccharomyces cerevisiae.
Mol Genet Genomics. 2009 Jul;282(1):25-35. doi: 10.1007/s00438-009-0443-9. Epub 2009 Mar 22.
10
The heterochromatin protein Swi6/HP1 activates replication origins at the pericentromeric region and silent mating-type locus.
Nat Cell Biol. 2009 Mar;11(3):357-62. doi: 10.1038/ncb1845. Epub 2009 Feb 1.
Zotero 插件