The Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, California 90095-8346, USA.
Depress Anxiety. 2010 Apr;27(4):381-9. doi: 10.1002/da.20622.
Panic disorder (PD) is a highly prevalent and disabling condition, and subthreshold cases may be even more prevalent. This study examined psychiatric comorbidities, work functioning, and health-care utilization of individuals with subthreshold panic. The purpose of this study was to add to the accumulating evidence of significant comorbidity and disability associated with subthreshold PD.
Data are drawn from the Health Care for Communities study, a national household survey of the United States' adult, civilian, noninstitutionalized population (N=9585). Data assessing psychiatric disorders, employment and work productivity, and health-care utilization were collected. Seven categories of panic and subthreshold panic were created.
The prevalence of clinical and subthreshold panic in the general population was 40%. Subthreshold panic was associated with increased odds of several comorbid disorders, including depression, dysthymia, psychosis, generalized anxiety disorder, bipolar disorder, and alcohol and drug use disorders. Subthreshold panic was also associated with greater likelihood of health-care service utilization but not with the intensity of mental health services.
Psychiatric comorbidities and health-care utilization are common among patients with subthreshold panic. The relationship between varying degrees of panic symptomology and other mental health problems and indices of functioning impairment warrants further investigation. These results inform further research focusing on the course of subthreshold PD and its impact on quality of life.
恐慌症(PD)是一种高度流行且致残的疾病,而亚阈值病例可能更为普遍。本研究调查了亚阈值惊恐症患者的精神共病、工作功能和医疗保健利用情况。本研究的目的是增加与亚阈值 PD 相关的大量共病和残疾的证据。
数据来自社区医疗保健研究,这是一项对美国成年、平民、非机构化人口的全国性家庭调查(N=9585)。收集了评估精神障碍、就业和工作生产力以及医疗保健利用情况的数据。创建了七个恐慌和亚阈值恐慌类别。
在普通人群中,临床和亚阈值恐慌的患病率为 40%。亚阈值惊恐症与多种共病障碍的几率增加有关,包括抑郁症、心境恶劣障碍、精神病、广泛性焦虑障碍、双相情感障碍以及酒精和药物使用障碍。亚阈值惊恐症也与更有可能使用医疗保健服务有关,但与心理健康服务的强度无关。
亚阈值惊恐症患者常见精神共病和医疗保健利用。恐慌症状严重程度不同与其他心理健康问题和功能障碍指标之间的关系值得进一步研究。这些结果为进一步研究亚阈值 PD 的病程及其对生活质量的影响提供了信息。