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转诊至巴西一家急救医院毒理学科室的儿童及青少年意外中毒情况

ACCIDENTAL POISONING IN CHILDREN AND ADOLESCENTS ADMITTED TO A REFERRAL TOXICOLOGY DEPARTMENT OF A BRAZILIAN EMERGENCY HOSPITAL.

作者信息

Vilaça Luciana, Volpe Fernando Madalena, Ladeira Roberto Marini

机构信息

Fundação Hospitalar do Estado de Minas Gerais, Belo Horizonte, MG, Brazil.

出版信息

Rev Paul Pediatr. 2019 Nov 25;38:e2018096. doi: 10.1590/1984-0462/2020/38/2018096. eCollection 2020.

Abstract

OBJECTIVE

To describe the profile of children and adolescents admitted for exogenous unintentional poisoning in the emergency room and analyze factors associated with subsequent in-hospital admissions.

METHODS

This is a cross-sectional study based on hospital records of all subjects up to 19 years-old admitted in 2013 at a specialized toxicology service on a major public emergency hospital due to unintentional intoxication (as reported). Accidents with poisonous animals and insects were excluded. Percentages and frequencies were calculated for the qualitative variables, and measures of central tendency and dispersion for the continuous quantitative variables. Multivariate analysis was performed using binary logistic regression to identify variables associated with subsequent in-hospital admissions.

RESULTS

In 2013, 353 cases were reported. Poisonings were more frequent in children 0-4 years-old (72.5%) and in boys (55%). The vast majority was of dwellers of the Metropolitan Region of Belo Horizonte (83%), and 90% of the accidental poisonings occurred at home. 82.7% of the poisonings occurred by oral ingestion, especially of medicinal (36.5%) and cleaning products (29.4% of all poisonings). Only 12.2% of the cases resulted in hospitalization, and only one resulted in death. Residing outside Belo Horizonte (OR=5.20 [95%CI 2.37-11.44]) and poisoning by two or more products (OR=4.29 [95%CI 1.33-13.82]) were considered risk factors for hospitalization.

CONCLUSIONS

Accidental poisonings occurred most frequently by ingestion of household medications and cleaning products, especially among children under 4 years-old. Preventive strategies should be primarily directed for this prevalent profile.

摘要

目的

描述急诊室收治的因外源性非故意中毒的儿童和青少年概况,并分析与随后住院相关的因素。

方法

这是一项横断面研究,基于2013年一家大型公共急诊医院专门毒理学服务部门收治的所有19岁以下因非故意中毒(如报告所述)的患者的医院记录。排除有毒动物和昆虫导致的事故。计算定性变量的百分比和频率,以及连续定量变量的集中趋势和离散度测量值。使用二元逻辑回归进行多变量分析,以确定与随后住院相关的变量。

结果

2013年报告了353例病例。中毒在0至4岁儿童中更为常见(72.5%),在男孩中更为常见(55%)。绝大多数是贝洛奥里藏特大都市区的居民(83%),90%的意外中毒发生在家中。82.7%的中毒是通过口服摄入,尤其是药物(36.5%)和清洁产品(占所有中毒的29.4%)。只有12.2%的病例导致住院,只有1例导致死亡。居住在贝洛奥里藏特以外地区(比值比=5.20[95%置信区间2.37-11.44])和由两种或更多产品中毒(比值比=4.29[95%置信区间1.33-13.82])被认为是住院的危险因素。

结论

意外中毒最常见的原因是摄入家用药物和清洁产品,尤其是在4岁以下儿童中。预防策略应主要针对这种普遍情况。

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