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Oral bicarbonate: renoprotective in CKD?

作者信息

Kovesdy Csaba P, Kalantar-Zadeh Kamyar

出版信息

Nat Rev Nephrol. 2010 Jan;6(1):15-7. doi: 10.1038/nrneph.2009.204.

DOI:10.1038/nrneph.2009.204
PMID:20023686
Abstract
摘要

相似文献

1
Oral bicarbonate: renoprotective in CKD?口服碳酸氢盐：对慢性肾脏病有肾脏保护作用吗？
Nat Rev Nephrol. 2010 Jan;6(1):15-7. doi: 10.1038/nrneph.2009.204.
2
The effect of sodium bicarbonate on cytokine secretion in CKD patients with metabolic acidosis.碳酸氢钠对代谢性酸中毒的慢性肾脏病患者细胞因子分泌的影响。
Biomed Pharmacother. 2015 Apr;71:98-101. doi: 10.1016/j.biopha.2015.02.012. Epub 2015 Feb 26.
3
In older adults with CKD and mild acidosis, oral sodium bicarbonate did not improve physical function.在患有 CKD 和轻度酸中毒的老年患者中，口服碳酸氢钠并未改善其身体功能。
Ann Intern Med. 2020 Nov 17;173(10):JC56. doi: 10.7326/ACPJ202011170-056.
4
A prospective, multicenter, randomized, controlled study: the correction of metabolic acidosis with use of bicarbonate in Chronic Renal Insufficiency (UBI) Study.一项前瞻性、多中心、随机、对照研究：慢性肾功能不全患者（UBI 研究）使用碳酸氢盐纠正代谢性酸中毒。
J Nephrol. 2012 May-Jun;25(3):437-40. doi: 10.5301/jn.5000014.
5
Approach to the Treatment of Chronic Metabolic Acidosis in CKD.慢性肾脏病中慢性代谢性酸中毒的治疗方法。
Am J Kidney Dis. 2016 Apr;67(4):696-702. doi: 10.1053/j.ajkd.2015.12.016. Epub 2016 Jan 6.
6
Treatment of acidosis in CKD.
Clin J Am Soc Nephrol. 2013 Mar;8(3):342-3. doi: 10.2215/CJN.00240113. Epub 2013 Jan 31.
7
Sodium Bicarbonate Treatment and Clinical Outcomes in Chronic Kidney Disease with Metabolic Acidosis: A Meta-Analysis.碳酸氢钠治疗代谢性酸中毒的慢性肾脏病患者的临床结局：一项荟萃分析。
Clin J Am Soc Nephrol. 2024 Aug 1;19(8):959-969. doi: 10.2215/CJN.0000000000000487. Epub 2024 Jul 9.
8
Oral Sodium Bicarbonate Supplementation Does Not Affect Serum Calcification Propensity in Patients with Chronic Kidney Disease and Chronic Metabolic Acidosis.口服碳酸氢钠补充剂不会影响慢性肾脏病和慢性代谢性酸中毒患者的血清钙化倾向。
Kidney Blood Press Res. 2019;44(2):188-199. doi: 10.1159/000498975. Epub 2019 May 8.
9
Treatment of metabolic acidosis with sodium bicarbonate delays progression of chronic kidney disease: the UBI Study.用碳酸氢钠治疗代谢性酸中毒会延缓慢性肾脏病的进展：UBI 研究。
J Nephrol. 2019 Dec;32(6):989-1001. doi: 10.1007/s40620-019-00656-5. Epub 2019 Oct 9.
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Successful correction of metabolic acidosis is difficult to achieve in chronic kidney disease.在慢性肾脏病中，很难成功纠正代谢性酸中毒。
Nefrologia (Engl Ed). 2020 May-Jun;40(3):328-335. doi: 10.1016/j.nefro.2019.09.006. Epub 2019 Dec 18.

引用本文的文献

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New solutions to old problems-metabolic acidosis in chronic kidney disease.慢性肾脏病中旧问题的新解决方案——代谢性酸中毒
Ann Transl Med. 2020 Oct;8(19):1256. doi: 10.21037/atm-2020-70.
2
Bicarbonate Therapy for Critically Ill Patients with Metabolic Acidosis: A Systematic Review.碳酸氢盐治疗重症代谢性酸中毒患者：一项系统评价
Cureus. 2019 Mar 22;11(3):e4297. doi: 10.7759/cureus.4297.
3
Oral alkali therapy and the management of metabolic acidosis of chronic kidney disease: A narrative literature review.口服碱疗法与慢性肾脏病代谢性酸中毒的管理：一项叙述性文献综述

本文引用的文献

1
Bicarbonate supplementation slows progression of CKD and improves nutritional status.补充碳酸氢盐可减缓慢性肾脏病的进展并改善营养状况。
J Am Soc Nephrol. 2009 Sep;20(9):2075-84. doi: 10.1681/ASN.2008111205. Epub 2009 Jul 16.
2
Outcome predictability of biomarkers of protein-energy wasting and inflammation in moderate and advanced chronic kidney disease.中晚期慢性肾脏病患者蛋白质能量消耗和炎症生物标志物的预后可预测性
Am J Clin Nutr. 2009 Aug;90(2):407-14. doi: 10.3945/ajcn.2008.27390. Epub 2009 Jun 17.
3
Association of serum bicarbonate levels with mortality in patients with non-dialysis-dependent CKD.
World J Nephrol. 2018 Oct 10;7(6):117-122. doi: 10.5527/wjn.v7.i6.117.
4
Regulation and function of the SLC38A3/SNAT3 glutamine transporter.SLC38A3/SNAT3谷氨酰胺转运体的调控与功能
Channels (Austin). 2016 Nov;10(6):440-52. doi: 10.1080/19336950.2016.1207024. Epub 2016 Jun 30.
5
The Envy of Scholars: Applying the Lessons of the Framingham Heart Study to the Prevention of Chronic Kidney Disease.学者们的羡慕：将弗雷明汉心脏研究的经验教训应用于慢性肾脏病的预防
Rambam Maimonides Med J. 2015 Jul 30;6(3):e0029. doi: 10.5041/RMMJ.10214.
6
Sodium bicarbonate therapy in patients with metabolic acidosis.代谢性酸中毒患者的碳酸氢钠治疗
ScientificWorldJournal. 2014;2014:627673. doi: 10.1155/2014/627673. Epub 2014 Oct 21.
7
Reduction of proteinuria through podocyte alkalinization.通过足细胞碱化降低蛋白尿
J Biol Chem. 2014 Jun 20;289(25):17454-67. doi: 10.1074/jbc.M114.568998. Epub 2014 May 9.
8
Anti-Inflammatory and Anti-Oxidative Nutrition in Hypoalbuminemic Dialysis Patients (AIONID) study: results of the pilot-feasibility, double-blind, randomized, placebo-controlled trial.低白蛋白血症透析患者抗炎抗氧化营养（AIONID）研究：初步可行性、双盲、随机、安慰剂对照试验的结果。
J Cachexia Sarcopenia Muscle. 2013 Dec;4(4):247-57. doi: 10.1007/s13539-013-0115-9. Epub 2013 Sep 20.
9
Let them eat during dialysis: an overlooked opportunity to improve outcomes in maintenance hemodialysis patients.让他们在透析期间进食：改善维持性血液透析患者预后的被忽视的机会。
J Ren Nutr. 2013 May;23(3):157-63. doi: 10.1053/j.jrn.2012.11.001. Epub 2013 Jan 10.
10
Diets and enteral supplements for improving outcomes in chronic kidney disease.改善慢性肾脏病结局的饮食和肠内补充剂。
Nat Rev Nephrol. 2011 May 31;7(7):369-84. doi: 10.1038/nrneph.2011.60.
非透析依赖型慢性肾脏病患者血清碳酸氢盐水平与死亡率的关联
Nephrol Dial Transplant. 2009 Apr;24(4):1232-7. doi: 10.1093/ndt/gfn633. Epub 2008 Nov 17.
4
Serum and dialysate potassium concentrations and survival in hemodialysis patients.血液透析患者的血清和透析液钾浓度与生存率
Clin J Am Soc Nephrol. 2007 Sep;2(5):999-1007. doi: 10.2215/CJN.04451206. Epub 2007 Aug 16.
5
Milk alkali syndrome and the dynamics of calcium homeostasis.乳碱综合征与钙稳态动力学
Clin J Am Soc Nephrol. 2006 Jul;1(4):641-54. doi: 10.2215/CJN.01451005. Epub 2006 Apr 26.
6
Association between serum bicarbonate and death in hemodialysis patients: is it better to be acidotic or alkalotic?血液透析患者血清碳酸氢盐与死亡之间的关联：酸中毒还是碱中毒更好？
Clin J Am Soc Nephrol. 2006 Jan;1(1):70-8. doi: 10.2215/CJN.00010505. Epub 2005 Nov 23.
7
Risks of chronic metabolic acidosis in patients with chronic kidney disease.慢性肾脏病患者慢性代谢性酸中毒的风险
Kidney Int Suppl. 2005 Jun(95):S21-7. doi: 10.1111/j.1523-1755.2005.09503.x.
8
Metabolic acidosis and malnutrition-inflammation complex syndrome in chronic renal failure.慢性肾衰竭中的代谢性酸中毒与营养不良-炎症复合综合征
Semin Dial. 2004 Nov-Dec;17(6):455-65. doi: 10.1111/j.0894-0959.2004.17606.x.
9
Association of predialysis serum bicarbonate levels with risk of mortality and hospitalization in the Dialysis Outcomes and Practice Patterns Study (DOPPS).透析预后与实践模式研究（DOPPS）中透析前血清碳酸氢盐水平与死亡风险及住院风险的关联
Am J Kidney Dis. 2004 Oct;44(4):661-71.
10
Pathophysiology of chronic tubulo-interstitial disease in rats. Interactions of dietary acid load, ammonia, and complement component C3.大鼠慢性肾小管间质性疾病的病理生理学。饮食酸负荷、氨与补体成分C3的相互作用。
J Clin Invest. 1985 Aug;76(2):667-75. doi: 10.1172/JCI112020.