Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371.
Org Lett. 2010 Jan 15;12(2):352-5. doi: 10.1021/ol9026232.
An immense effort has been made to develop an efficient strategy for the carbon-carbon bond formation between aldehyde and nitrile intramolecularly using an N-heterocyclic carbene catalyst to derive 3-aminochromone derivatives in good to excellent yields (80-95%).
人们已经做出了巨大的努力，开发了一种有效的策略，使用 N-杂环卡宾催化剂实现醛和腈的分子内碳-碳键形成，以得到 3-氨基色酮衍生物，产率良好至优秀（80-95%）。
