Division of Etiology, Department of Population Sciences, City of Hope, Duarte, CA 91010, USA.
Cancer. 2010 Feb 15;116(4):949-56. doi: 10.1002/cncr.24843.
Cervical cancer incidence was evaluated by histologic type, age at diagnosis, and disease stage for 6 Asian ethnic groups residing in the United States.
Incidence rates were estimated for cervical squamous cell carcinoma (SCC) and adenocarcinoma by age and stage for 6 Asian ethnic groups-Asian Indian/Pakistani, Chinese, Filipino, Japanese, Korean, and Vietnamese-in 5 US cancer registry areas during 1996 through 2004. For comparison, rates among non-Hispanic whites, non-Hispanic blacks, and Hispanics were also calculated.
During 1996 through 2004, Vietnamese women had the highest (18.9 per 100,000) and Asian Indian/Pakistani women had the lowest (4.5) incidence of cervical cancer; this pattern was consistent by histologic type. Vietnamese women also had the highest incidence for localized (7.3) and regional (5.7) SCC and for localized (2.4) adenocarcinoma. Contrary to the plateau of SCC incidence apparent among white women by age 45 years, SCC rates continued to rise with age among Chinese, Filipina, Korean, and Vietnamese women.
There exists large variation in invasive cervical cancer incidence patterns among Asian ethnic groups in the United States and in comparison with rates for blacks, Hispanics, and whites. Early detection and prevention strategies for cervical cancer among Asians require targeted strategies by ethnic group.
通过组织学类型、诊断时的年龄和疾病阶段，评估了居住在美国的 6 个亚洲族群的宫颈癌发病率。
在 1996 年至 2004 年期间，在美国 5 个癌症登记处，按年龄和疾病阶段对 6 个亚洲族群（亚裔印度/巴基斯坦人、中国人、菲律宾人、日本人、韩国人和越南人）的宫颈鳞状细胞癌（SCC）和腺癌的发病率进行了估计。为了进行比较，还计算了非西班牙裔白种人、非西班牙裔黑人和西班牙裔的发病率。
在 1996 年至 2004 年期间，越南女性的宫颈癌发病率最高（18.9/100000），而亚裔印度/巴基斯坦女性的发病率最低（4.5）；这种模式在组织学类型上是一致的。越南女性的局部（7.3）和区域（5.7）SCC 以及局部（2.4）腺癌发病率也最高。与白人女性在 45 岁时 SCC 发病率明显呈平台状不同，中国、菲律宾、韩国和越南女性的 SCC 发病率随着年龄的增长而继续上升。
在美国，亚洲族群的浸润性宫颈癌发病率模式存在很大差异，与黑种人、西班牙裔和白种人的发病率相比也是如此。针对亚洲人的宫颈癌早期检测和预防策略需要针对特定族群制定有针对性的策略。
