Enamine-iminium 离子 Nazarov 环化反应的α-酮烯酮。
Enamine-iminium ion Nazarov cyclization of alpha-ketoenones.
机构信息
Department of Chemistry, 2545 The Mall, University of Hawaii, Honolulu, Hawaii 96822, USA.
出版信息
Org Lett. 2010 Feb 5;12(3):440-3. doi: 10.1021/ol9025765.
Abstract
The mono-triflate salts of some chiral nonracemic 1,2-diamines react with alpha-ketoenones in a stoichiometric reaction to form products of the Nazarov cyclization in high enantiomeric ratios. The mechanism appears to involve rearrangement of an enamine-iminium ion.
摘要
一些手性非外消旋 1,2-二胺的单三氟甲磺酸酯与α-酮烯酮在化学计量反应中反应，以高对映选择性形成 Nazarov 环化产物。该机理似乎涉及烯胺-亚胺离子的重排。
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