Sly P D, Lanteri C J, Raven J M
Department of Thoracic Medicine, Royal Children's Hospital, Melbourne, Victoria, Australia.
Pediatr Pulmonol. 1991;10(1):36-9. doi: 10.1002/ppul.1950100108.
Wheezy infants, less than 6 months of age, were given either inhaled salbutamol or saline in a double-blind study. A significant change in maximal flow at functional residual capacity (VmaxFRC) was defined as being greater than twice the coefficient of variation of the baseline measurements. There was no difference in the infants' response to saline or salbutamol. Wheezy infants, less than 6 months of age, do not have an increase in VmaxFRC following a single dose of inhaled salbutamol.
在一项双盲研究中，对6个月以下的喘息性婴儿给予吸入沙丁胺醇或生理盐水。功能残气量时的最大流速（VmaxFRC）的显著变化定义为大于基线测量变异系数的两倍。婴儿对生理盐水或沙丁胺醇的反应没有差异。6个月以下的喘息性婴儿单次吸入沙丁胺醇后VmaxFRC没有增加。
