Department of Biomedical Engineering, University of Southern California, 1042 Downey way, #140, Los Angeles, CA 90089, USA.
Ann Biomed Eng. 2010 Mar;38(3):707-13. doi: 10.1007/s10439-009-9876-x. Epub 2009 Dec 24.
We report the use of a multi-layer printed coil circuit for powering (36-94 mW) an implantable microbolus infusion pump (MIP) that can be activated remotely for use in drug infusion in nontethered, freely moving small animals. This implantable device provides a unique experimental tool with applications in the fields of animal behavior, pharmacology, physiology, and functional brain imaging. Two different designs are described: a battery-less pump usable when the animal is inside a home-cage surrounded by a primary inductive coil and a pump powered by a rechargeable battery that can be used for studies outside the home-cage. The use of printed coils for powering of small devices by inductive power transfer presents significant advantages over similar approaches using hand-wound coils in terms of ease of manufacturing and uniformity of design. The high efficiency of a class-E oscillator allowed powering of the minipumps without the need for close physical contact of the primary and secondary coils, as is currently the case for most devices powered by inductive power transfer.
我们报告了一种多层印刷线圈电路的使用，该电路可用于为可植入微滴输注泵 (MIP) 供电（36-94 毫瓦），该泵可远程激活，用于在无束缚、自由移动的小动物中进行药物输注。这种可植入装置为动物行为、药理学、生理学和功能脑成像等领域的应用提供了独特的实验工具。本文描述了两种不同的设计：一种是无电池的泵，可在动物被置于一个由初级感应线圈环绕的家庭笼内时使用；另一种是由可充电电池供电的泵，可用于家庭笼外的研究。与使用手工绕制线圈的类似方法相比，使用印刷线圈通过感应功率传输为小型设备供电具有显著的优势，因为它在制造和设计的一致性方面更加简单。类 E 振荡器的高效率允许无需初级和次级线圈的紧密物理接触即可为微型泵供电，而目前大多数通过感应功率传输供电的设备都需要这种接触。
