Epidemic Intelligence Service, Office of Workforce and Career Development, Division of Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.
Am J Obstet Gynecol. 2010 May;202(5):443.e1-6. doi: 10.1016/j.ajog.2009.10.865. Epub 2009 Dec 29.
We estimated the prevalence and patterns of herbal use among US women before and during pregnancy.
The National Birth Defects Prevention Study is an ongoing, population-based, case-control study. This analysis included 4239 women from 10 centers in the United States who delivered infants without major birth defects from 1998-2004.
The prevalence of reported herbal use 3 months before or during pregnancy was 10.9%. During pregnancy, prevalence was 9.4% and was highest in the first trimester. Higher prevalence was associated with age greater than 30 years and education greater than 12 years. Use varied considerably by state (5-17%). Ginger and ephedra were the most commonly reported products early in pregnancy; teas and chamomile were most commonly reported throughout pregnancy.
Potentially 395,000 US births annually involve antenatal exposure to herbal products. Health care providers should inquire routinely about herbal use and educate patients about what little is known regarding risks of these products.
评估美国女性在怀孕前和怀孕期间使用草药的流行情况和模式。
国家出生缺陷预防研究是一项正在进行的、基于人群的病例对照研究。本分析包括来自美国 10 个中心的 4239 名妇女,她们在 1998-2004 年间分娩了无重大出生缺陷的婴儿。
报告的怀孕前 3 个月或怀孕期间使用草药的流行率为 10.9%。怀孕期间的流行率为 9.4%,在孕早期最高。较高的使用率与年龄大于 30 岁和教育程度大于 12 年有关。各州的使用率差异很大(5-17%)。在怀孕早期,最常报告使用的产品是生姜和麻黄;在整个怀孕期间,最常报告使用的产品是茶和甘菊。
每年可能有 395,000 例美国分娩涉及产前接触草药产品。医疗保健提供者应常规询问草药使用情况,并教育患者了解这些产品的风险知之甚少。