新鲜小麦草汁对正常大鼠血脂谱的影响。
Effect of fresh Triticum aestivum grass juice on lipid profile of normal rats.
机构信息
Department of Pharmacology, Gajara Raja Medical College, Gwalior - 474 001, India.
出版信息
Indian J Pharmacol. 2008 Oct;40(5):235-6. doi: 10.4103/0253-7613.44157.
OBJECTIVE
To study the hypolipidemic activity of fresh grass juice of Triticum aestivum in normal rats.
MATERIALS AND METHODS
Freshly prepared Triticum aestivum grass juice was administered to normal rats at the dose of 5 ml/kg and 10 ml/kg orally once daily for 21 days. Blood samples were collected after 24 hours of last administration and used for estimation of lipid profile. Fresh grass juice was also subjected to preliminary phytochemical screening.
RESULTS
Fresh grass juice administration produced dose related significant (P < 0.05) reduction in total chloesterol, triglycerides, low density lipoprotein-cholesterol and very low density lipoprotein-cholesterol levels in normal rats as compared to control. Preliminary phytochemical screening revealed presence of alkaloids, tannins, saponins and sterols in Triticum aestivum grass.
CONCLUSION
The results of the present study lndicate hypolipidemic activity of fresh Triticum aestivum grass juice.
目的
研究普通大鼠中小麦鲜草汁的降血脂活性。
材料与方法
将新鲜制备的小麦鲜草汁以 5ml/kg 和 10ml/kg 的剂量每天口服一次给予正常大鼠，共 21 天。末次给药后 24 小时采集血样，用于估计血脂谱。新鲜草汁也进行了初步的植物化学成分筛选。
结果
与对照组相比，小麦鲜草汁给药可使正常大鼠的总胆固醇、甘油三酯、低密度脂蛋白胆固醇和极低密度脂蛋白胆固醇水平呈剂量相关性显著降低（P<0.05）。初步的植物化学成分筛选显示，小麦草中含有生物碱、单宁、皂苷和固醇。
结论
本研究结果表明，新鲜小麦草汁具有降血脂活性。
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