Cho Kyoung-Suok, Kang Suk-Gu, Yoo Do-Sung, Huh Pil-Woo, Kim Dal-Soo, Lee Sang-Bok
Department of Neurosurgery, Uijeongbu St. Mary's Hospital, The Catholic University College of Medicine, Uijeongbu, Korea.
J Korean Neurosurg Soc. 2009 Nov;46(5):425-30. doi: 10.3340/jkns.2009.46.5.425. Epub 2009 Nov 30.
The present study analyzed the risk factors, prevalence and clinical results following revision surgery for adjacent segment degeneration (ASD) in patients who had undergone lumbar fusion.
Over an 8-year period, we performed posterior lumbar fusion in 81 patients. Patients were followed a minimum of 2 years (mean 5.5 years). During that time, 9 patients required revision surgery due to ASD development. Four patients underwent autogenous posterolateral arthrodesis and extended transpedicle screw fixation, 4 patients underwent decompressive laminectomy and interspinous device implantation, and 1 patient underwent simple decompression.
Of the 9 of patients with clinical ASD, 33.3% (3 of 9) of patients did not have radiographic ASD on plain radiographs. Following revision surgery, the clinical results were excellent or good in 8 patients (88.9%). Age > 50 years at primary surgery was a significant risk factor for ASD development, while number of fusion levels, initial diagnosis and type of fusion were not.
The incidence of ASD development after lumbar surgery was 11.1% (9 of 81) in this study. Age greater than 50 was the statistically significant risk factor for ASD development. Similar successful clinical outcomes were observed after extended fusion with wide decompression or after interspinous device implantation. Given the latter procedure is less invasive, the findings suggest it may be considered a treatment alternative in selected cases but it needs further study.
本研究分析了接受腰椎融合术的患者相邻节段退变(ASD)翻修手术后的危险因素、患病率及临床结果。
在8年期间,我们对81例患者进行了后路腰椎融合术。患者至少随访2年(平均5.5年)。在此期间,9例患者因ASD进展需要翻修手术。4例患者接受了自体后外侧关节融合术及延长椎弓根螺钉固定,4例患者接受了减压性椎板切除术及棘突间装置植入,1例患者接受了单纯减压。
在9例临床诊断为ASD的患者中,33.3%(9例中的3例)患者在X线平片上没有影像学ASD表现。翻修手术后,8例患者(88.9%)的临床结果为优或良。初次手术时年龄>50岁是ASD发生的一个显著危险因素,而融合节段数、初始诊断及融合类型则不是。
本研究中腰椎手术后ASD的发生率为11.1%(81例中的9例)。年龄大于50岁是ASD发生的统计学显著危险因素。广泛减压的延长融合术或棘突间装置植入术后观察到了相似的成功临床结果。鉴于后一种手术创伤较小,研究结果表明在某些病例中可将其视为一种治疗选择,但还需要进一步研究。