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One-year outcome evaluation after interspinous implantation for degenerative spinal stenosis with segmental instability.经椎间植入治疗伴有节段性不稳的退变性腰椎管狭窄症的一年期疗效评估
J Korean Med Sci. 2007 Apr;22(2):330-5. doi: 10.3346/jkms.2007.22.2.330.
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Adjacent segment degeneration in the lumbar spine.腰椎相邻节段退变
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A prospective randomized multi-center study for the treatment of lumbar spinal stenosis with the X STOP interspinous implant: 1-year results.一项使用X STOP棘突间植入物治疗腰椎管狭窄症的前瞻性随机多中心研究:1年结果。
Eur Spine J. 2004 Feb;13(1):22-31. doi: 10.1007/s00586-003-0581-4. Epub 2003 Dec 19.
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The fate of the adjacent motion segments after lumbar fusion.腰椎融合术后相邻运动节段的转归。
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Correlation between sagittal plane changes and adjacent segment degeneration following lumbar spine fusion.腰椎融合术后矢状面变化与相邻节段退变的相关性
Eur Spine J. 2001 Aug;10(4):314-9. doi: 10.1007/s005860000239.
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Comparative study of the incidence and severity of degenerative change in the transition zones after instrumented versus noninstrumented fusions of the lumbar spine.腰椎融合手术中,使用内固定与未使用内固定情况下,融合节段退变改变的发生率及严重程度的对比研究
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Lumbar fusion results related to diagnosis.腰椎融合术的结果与诊断相关。
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The effect of spinal destabilization and instrumentation on lumbar intradiscal pressure: an in vitro biomechanical analysis.脊柱失稳与内固定对腰椎椎间盘内压力的影响:一项体外生物力学分析。
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腰椎融合术后症状性相邻节段退变的危险因素及手术治疗

Risk factors and surgical treatment for symptomatic adjacent segment degeneration after lumbar spine fusion.

作者信息

Cho Kyoung-Suok, Kang Suk-Gu, Yoo Do-Sung, Huh Pil-Woo, Kim Dal-Soo, Lee Sang-Bok

机构信息

Department of Neurosurgery, Uijeongbu St. Mary's Hospital, The Catholic University College of Medicine, Uijeongbu, Korea.

出版信息

J Korean Neurosurg Soc. 2009 Nov;46(5):425-30. doi: 10.3340/jkns.2009.46.5.425. Epub 2009 Nov 30.

DOI:10.3340/jkns.2009.46.5.425
PMID:20041051
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2796347/
Abstract

OBJECTIVE

The present study analyzed the risk factors, prevalence and clinical results following revision surgery for adjacent segment degeneration (ASD) in patients who had undergone lumbar fusion.

METHODS

Over an 8-year period, we performed posterior lumbar fusion in 81 patients. Patients were followed a minimum of 2 years (mean 5.5 years). During that time, 9 patients required revision surgery due to ASD development. Four patients underwent autogenous posterolateral arthrodesis and extended transpedicle screw fixation, 4 patients underwent decompressive laminectomy and interspinous device implantation, and 1 patient underwent simple decompression.

RESULTS

Of the 9 of patients with clinical ASD, 33.3% (3 of 9) of patients did not have radiographic ASD on plain radiographs. Following revision surgery, the clinical results were excellent or good in 8 patients (88.9%). Age > 50 years at primary surgery was a significant risk factor for ASD development, while number of fusion levels, initial diagnosis and type of fusion were not.

CONCLUSION

The incidence of ASD development after lumbar surgery was 11.1% (9 of 81) in this study. Age greater than 50 was the statistically significant risk factor for ASD development. Similar successful clinical outcomes were observed after extended fusion with wide decompression or after interspinous device implantation. Given the latter procedure is less invasive, the findings suggest it may be considered a treatment alternative in selected cases but it needs further study.

摘要

目的

本研究分析了接受腰椎融合术的患者相邻节段退变(ASD)翻修手术后的危险因素、患病率及临床结果。

方法

在8年期间,我们对81例患者进行了后路腰椎融合术。患者至少随访2年(平均5.5年)。在此期间,9例患者因ASD进展需要翻修手术。4例患者接受了自体后外侧关节融合术及延长椎弓根螺钉固定,4例患者接受了减压性椎板切除术及棘突间装置植入,1例患者接受了单纯减压。

结果

在9例临床诊断为ASD的患者中,33.3%(9例中的3例)患者在X线平片上没有影像学ASD表现。翻修手术后,8例患者(88.9%)的临床结果为优或良。初次手术时年龄>50岁是ASD发生的一个显著危险因素,而融合节段数、初始诊断及融合类型则不是。

结论

本研究中腰椎手术后ASD的发生率为11.1%(81例中的9例)。年龄大于50岁是ASD发生的统计学显著危险因素。广泛减压的延长融合术或棘突间装置植入术后观察到了相似的成功临床结果。鉴于后一种手术创伤较小,研究结果表明在某些病例中可将其视为一种治疗选择,但还需要进一步研究。