甲型H1N1流感大流行病毒引起的有症状感染比季节性毒株引起的感染频率更低：安托万·弗拉奥、 Xavier de Lamballerie、卡米尔·佩拉特、尼古拉·萨莱、托马斯·汉斯利克 。
Symptomatic infections less frequent with H1N1pdm than with seasonal strains: Antoine Flahault, Xavier de Lamballerie, Camille Pelat, Nicolas Salez, Thomas Hanslik.
作者信息
Flahault Antoine, de Lamballerie Xavier, Hanslik Thomas
机构信息
EHESP School of Public Health and Université Versailles Saint Quentin.
出版信息
PLoS Curr. 2009 Dec 24;1:RRN1140. doi: 10.1371/currents.rrn1140.
Abstract
A serosurvey conducted in a sample of first quarter pregnant women in France at week 48-49 of 2009 exhibit a seroprevalence level of 10.6%. It has been extrapolated in male and female population living in France mainland, aged 20-39 yr, that 1,712,000, 95%CI (1,112,700 - 2,311,300) people were recently infected by H1N1pdm (recently vaccinated women were excluded from analysis). From week 36 to 46-47 of 2009, 336,288, 95%CI (207,303-421,299) patients visited their general practitioners with clinical influenza in France, mainland. We then extrapolated the proportion of symptomatic H1N1pdm influenza in both males and females aged 20-39 yr who visited their GP to be 19.6%.
摘要
2009年第48 - 49周，在法国第一季度孕妇样本中进行的血清学调查显示血清阳性率为10.6%。据推断，在法国大陆年龄为20 - 39岁的男性和女性人群中，有171.2万人，95%置信区间（111.27万 - 231.13万）最近感染了甲型H1N1流感病毒（分析中排除了近期接种疫苗的女性）。2009年第36周到46 - 47周期间，在法国大陆有336288名，95%置信区间（207303 - 421299）患者因临床流感症状就诊于全科医生处。然后我们推断，在就诊于全科医生的20 - 39岁男性和女性中，出现症状的甲型H1N1流感病毒感染比例为19.6%。
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