Machida Kazuhiro, Hirose Yoichiro, Fuse Shinichiro, Sugawara Tohru, Takahashi Takashi
Development Department, ChemGenesis Incorporated, Tokyo, Japan.
Chem Pharm Bull (Tokyo). 2010 Jan;58(1):87-93. doi: 10.1248/cpb.58.87.
In this paper we describe the development of a fully-automated solution-phase synthesizer, 'ChemKonzert' that can be used to prepare a wide variety of organic compounds. The automated synthesizer is ingeniously designed to perform most of the chemical reactions currently used by synthetic organic chemists and utilizes a centrifugal separator to efficiently achieve liquid-liquid extraction. The design of the hardware and software will be described in this paper, and several examples of organic reactions will also be presented as applications of the apparatus.
在本文中，我们描述了一种全自动溶液相合成仪“ChemKonzert”的开发，该合成仪可用于制备多种有机化合物。该自动合成仪设计巧妙，能够执行目前合成有机化学家所使用的大多数化学反应，并利用离心分离器高效地实现液 - 液萃取。本文将介绍硬件和软件的设计，还将给出几个有机反应的例子作为该仪器的应用。
