Programa de Microbiología, Instituto de Ciencias Biomédicas, Facultad de Medicina Universidad de Chile, and 2Consultorio Agustín Cruz Melo, Independencia, Santiago, Chile.
Clin Infect Dis. 2010 Feb 1;50(3):e19-21. doi: 10.1086/649869.
The presence of Pneumocystis was assessed in oropharyngeal wash specimens from 110 adults (median age, 76 years; age range, 69-95 years), 66 of whom had a paired nasal swab specimen. Pneumocystis jirovecii DNA was detected in 12.8% of oropharyngeal wash specimens, and the frequency increased to 21.5% in paired specimens. Pneumocystis colonization is prevalent in older adults. Double noninvasive sampling increases the diagnostic yield.
对 110 名成人（中位年龄 76 岁；年龄范围 69-95 岁）的口咽冲洗标本进行了肺囊虫检测，其中 66 人有配对的鼻拭子标本。在 12.8%的口咽冲洗标本中检测到耶氏肺孢子菌 DNA，在配对标本中该频率增加至 21.5%。肺囊虫定植在老年人中很普遍。双重非侵入性采样可提高诊断产量。
