老年人肺孢子菌定植与单次和多次非侵入性呼吸采样的诊断效果比较。
Pneumocystis colonization in older adults and diagnostic yield of single versus paired noninvasive respiratory sampling.
机构信息
Programa de Microbiología, Instituto de Ciencias Biomédicas, Facultad de Medicina Universidad de Chile, and 2Consultorio Agustín Cruz Melo, Independencia, Santiago, Chile.
出版信息
Clin Infect Dis. 2010 Feb 1;50(3):e19-21. doi: 10.1086/649869.
The presence of Pneumocystis was assessed in oropharyngeal wash specimens from 110 adults (median age, 76 years; age range, 69-95 years), 66 of whom had a paired nasal swab specimen. Pneumocystis jirovecii DNA was detected in 12.8% of oropharyngeal wash specimens, and the frequency increased to 21.5% in paired specimens. Pneumocystis colonization is prevalent in older adults. Double noninvasive sampling increases the diagnostic yield.
对 110 名成人（中位年龄 76 岁；年龄范围 69-95 岁）的口咽冲洗标本进行了肺囊虫检测，其中 66 人有配对的鼻拭子标本。在 12.8%的口咽冲洗标本中检测到耶氏肺孢子菌 DNA，在配对标本中该频率增加至 21.5%。肺囊虫定植在老年人中很普遍。双重非侵入性采样可提高诊断产量。
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