• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Systemic inflammation as a confounding factor in cancer biomarker discovery and validation.

作者信息

Chechlinska Magdalena, Kowalewska Magdalena, Nowak Radoslawa

机构信息

Department of Immunology, Maria Sklodowska-Curie Memorial Cancer Centre and Institute of Oncology, Warsaw, Poland.

出版信息

Nat Rev Cancer. 2010 Jan;10(1):2-3. doi: 10.1038/nrc2782.

DOI:10.1038/nrc2782
PMID:20050335
Abstract
摘要

相似文献

1
Systemic inflammation as a confounding factor in cancer biomarker discovery and validation.全身炎症作为癌症生物标志物发现与验证中的一个混杂因素。
Nat Rev Cancer. 2010 Jan;10(1):2-3. doi: 10.1038/nrc2782.
2
Multiplatform Integrative Analysis of Immunogenomic Data for Biomarker Discovery.用于生物标志物发现的免疫基因组数据的多平台综合分析
Methods Mol Biol. 2020;2055:679-698. doi: 10.1007/978-1-4939-9773-2_30.
3
Deregulation of apolipoprotein C2 gene in cancer: A potential metabolic vulnerability.癌症中载脂蛋白C2基因的失调：一种潜在的代谢易损性。
Clin Transl Med. 2021 Jun;11(6):e406. doi: 10.1002/ctm2.406.
4
Biomarker search illuminates cancer immune biology.生物标志物研究揭示癌症免疫生物学。
Nat Rev Drug Discov. 2016 Jun 30;15(7):443-5. doi: 10.1038/nrd.2016.131.
5
Systematic Pan-Cancer Analysis Identifies TREM2 as an Immunological and Prognostic Biomarker.系统泛癌症分析鉴定 TREM2 为一种免疫和预后生物标志物。
Front Immunol. 2021 Feb 17;12:646523. doi: 10.3389/fimmu.2021.646523. eCollection 2021.
6
Antibody validation of immunohistochemistry for biomarker discovery: recommendations of a consortium of academic and pharmaceutical based histopathology researchers.用于生物标志物发现的免疫组织化学抗体验证：一个由学术和制药领域的组织病理学研究人员组成的联盟的建议
Methods. 2014 Nov;70(1):34-8. doi: 10.1016/j.ymeth.2014.01.018. Epub 2014 Feb 11.
7
Implication of aberrant glycosylation in cancer and use of lectin for cancer biomarker discovery.异常糖基化在癌症中的意义及凝集素在癌症生物标志物发现中的应用。
Protein Pept Lett. 2009;16(5):499-507. doi: 10.2174/092986609788167798.
8
Clinical applications of PD-L1 bioassays for cancer immunotherapy.PD-L1 生物检测在癌症免疫治疗中的临床应用。
J Hematol Oncol. 2017 May 17;10(1):110. doi: 10.1186/s13045-017-0479-y.
9
Inflammation and Cancer.炎症与癌症。
Endocr Metab Immune Disord Drug Targets. 2021;21(2):193-194. doi: 10.2174/187153032102210105105653.
10
Modernized version of Todaro and De Larco's 1978 hypothesis on the autocrine nature of tumor growth.托达罗和德拉尔科1978年关于肿瘤生长自分泌性质假说的现代化版本。
J Natl Cancer Inst. 1996 Sep 4;88(17):1239-40. doi: 10.1093/jnci/88.17.1239.

引用本文的文献

1
Persistent and novel changes in plasma microRNA profiles in patients with non-small cell lung cancer following tumour resection.非小细胞肺癌患者肿瘤切除后血浆微小RNA谱的持续且新颖的变化
Transl Lung Cancer Res. 2025 Mar 31;14(3):677-706. doi: 10.21037/tlcr-24-626. Epub 2025 Mar 27.
2
The diversity of CD8 T cell dysfunction in cancer and viral infection.癌症和病毒感染中CD8 T细胞功能障碍的多样性。
Nat Rev Immunol. 2025 Apr 11. doi: 10.1038/s41577-025-01161-6.
3
Relating the molecular phenotype of ulcerative colitis to the clinical course.

本文引用的文献

1
Cancer: Inflaming metastasis.癌症：炎症促进转移。
Nature. 2009 Jan 1;457(7225):36-7. doi: 10.1038/457036b.
2
Detection of altered global DNA methylation in coronary artery disease patients.冠心病患者全基因组DNA甲基化改变的检测
DNA Cell Biol. 2008 Jul;27(7):357-65. doi: 10.1089/dna.2007.0694.
3
Detection of circulating cancer cells in lung cancer patients with a panel of marker genes.利用一组标记基因检测肺癌患者循环癌细胞
将溃疡性结肠炎的分子表型与临床病程相关联。
Sci Rep. 2025 Mar 11;15(1):8342. doi: 10.1038/s41598-025-90618-8.
4
Association between cardiometabolic index and all-cause and cause-specific mortality among the general population: NHANES 1999-2018.普通人群中心血管代谢指数与全因死亡率及特定病因死亡率之间的关联：1999 - 2018年美国国家健康与营养检查调查（NHANES）
Lipids Health Dis. 2024 Dec 27;23(1):425. doi: 10.1186/s12944-024-02408-2.
5
Association Between Systemic Immune-Inflammation Index and CA125 in Older Women: Insights from a Cross-Sectional NHANES Study.老年女性全身免疫炎症指数与CA125之间的关联：一项横断面美国国家健康与营养检查调查研究的见解
Int J Womens Health. 2024 Nov 27;16:1981-1991. doi: 10.2147/IJWH.S492712. eCollection 2024.
6
Preoperative serum cholinesterase as a prognostic factor in patients with colorectal cancer.术前血清胆碱酯酶作为结直肠癌患者的预后因素
Ann Gastroenterol Surg. 2024 Mar 18;8(4):650-659. doi: 10.1002/ags3.12794. eCollection 2024 Jul.
7
The Role of Cytokines in Cutaneous T Cell Lymphoma: A Focus on the State of the Art and Possible Therapeutic Targets.细胞因子在皮肤 T 细胞淋巴瘤中的作用：聚焦最新进展和可能的治疗靶点。
Cells. 2024 Mar 28;13(7):584. doi: 10.3390/cells13070584.
8
The pretherapeutic systemic inflammation score is a prognostic predictor for elderly patients with oesophageal cancer: a case control study.治疗前系统性炎症评分是老年食管癌患者的预后预测指标：一项病例对照研究。
BMC Cancer. 2023 Jun 4;23(1):505. doi: 10.1186/s12885-023-10982-4.
9
Clinical significance of prognostic nutritional index (PNI)-monocyte-to-lymphocyte ratio (MLR)-platelet (PLT) score on postoperative outcomes in non-metastatic clear cell renal cell carcinoma.预后营养指数（PNI）-单核细胞与淋巴细胞比值（MLR）-血小板（PLT）评分对非转移性透明细胞肾细胞癌术后结局的临床意义。
BMC Surg. 2023 May 10;23(1):117. doi: 10.1186/s12893-023-02001-x.
10
Research of Prostate Cancer Urinary Diagnostic Biomarkers by Proteomics: The Noteworthy Influence of Inflammation.蛋白质组学研究前列腺癌尿液诊断生物标志物：炎症的显著影响
Diagnostics (Basel). 2023 Apr 1;13(7):1318. doi: 10.3390/diagnostics13071318.
Biochem Biophys Res Commun. 2008 Aug 8;372(4):756-60. doi: 10.1016/j.bbrc.2008.05.101. Epub 2008 Jun 2.
4
Biomarker identification in human pancreatic cancer sera.人类胰腺癌血清中的生物标志物鉴定
Pancreas. 2008 Jan;36(1):61-9. doi: 10.1097/mpa.0b013e3180d0a738.
5
The relevance of RT-PCR detection of disseminated tumour cells is hampered by the expression of markers regarded as tumour-specific in activated lymphocytes.逆转录聚合酶链反应（RT-PCR）检测播散肿瘤细胞的相关性受到激活淋巴细胞中被视为肿瘤特异性标志物表达的阻碍。
Eur J Cancer. 2006 Nov;42(16):2671-4. doi: 10.1016/j.ejca.2006.05.036. Epub 2006 Sep 15.
6
Differential proteomic serum pattern of low molecular weight proteins expressed by adenocarcinoma lung cancer patients.腺癌肺癌患者表达的低分子量蛋白质的差异蛋白质组血清模式。
J Exp Ther Oncol. 2005;5(1):31-8.
7
Diagnosis of liver cancer using HPLC-based metabonomics avoiding false-positive result from hepatitis and hepatocirrhosis diseases.基于高效液相色谱的代谢组学用于肝癌诊断，避免肝炎和肝硬化疾病导致的假阳性结果。
J Chromatogr B Analyt Technol Biomed Life Sci. 2004 Dec 25;813(1-2):59-65. doi: 10.1016/j.jchromb.2004.09.032.
8
Quantitative real-time RT-PCR for detection of disseminated tumor cells in peripheral blood of patients with colorectal cancer using different mRNA markers.使用不同mRNA标志物通过定量实时逆转录聚合酶链反应检测结直肠癌患者外周血中的播散肿瘤细胞。
Int J Cancer. 2004 Jan 10;108(2):219-27. doi: 10.1002/ijc.11547.
9
Circulating DNA: a new diagnostic gold mine?循环DNA：一座新的诊断金矿？
Cancer Treat Rev. 2002 Oct;28(5):255-71. doi: 10.1016/s0305-7372(02)00077-4.
10
Transcription of cytokeratins 8, 18, and 19 in bone marrow and limited expression of cytokeratins 7 and 20 by carcinoma cells: inherent limitations for RT-PCR in the detection of isolated tumor cells.细胞角蛋白8、18和19在骨髓中的转录以及癌细胞中细胞角蛋白7和20的有限表达：RT-PCR检测孤立肿瘤细胞的内在局限性。
Lab Invest. 2001 Oct;81(10):1351-61. doi: 10.1038/labinvest.3780349.