Service de Réanimation, Centre Hospitalier de Versailles, 177 Rue de Versailles, 78157 Le Chesnay, France.
Neurocrit Care. 2010 Jun;12(3):400-2. doi: 10.1007/s12028-009-9319-4.
Alcoholic hand rubs (AHRs) have been proven effective in preventing nosocomial infections, and healthcare authorities include AHRs use among quality-of-care criteria. Since the onset of the influenza A (H1N1) pandemic, AHRs have gained considerable popularity among the general public.
We report a case of intentional AHRs self-poisoning inducing rapid coma with hyperlactatemia, and a full recovery. The relevant literature was reviewed. To our knowledge, this is the third reported case of intentional AHRs poisoning. 3 patients presented with a picture of acute alcohol intoxication, of variable severity depending on the amount ingested and speed of ingestion.
The blood alcohol level was 414 mg/dl and tests for other drugs were performed 30 min after admission. The blood lactate level increased briefly to 4.8 mmol/l, without renal or hepatic function disturbances. She regained consciousness after 6 h then achieved a full recovery allowing extubation and readmission to the psychiatric ward after 24 h. She reported gulping down the entire contents of the Aniosgel bottle.
Whereas overdrinking in social settings (wine and liquor) leads to a gradual increase in blood alcohol levels, AHRs poisoning is usually characterized by a sudden massive alcohol load. The unusual nature of the alcohol source may lead to diagnostic wanderings. AHRs are currently available in bottles that facilitate the ingestion of large amounts. Unit-dose packaging or dispensing might decrease the risk of AHRs poisoning.
酒精擦手液(AHRs)已被证明能有效预防医院感染,医疗保健当局将其使用纳入了护理质量标准。自甲型 H1N1 流感大流行以来,AHRs 在公众中变得非常流行。
我们报告了一例故意使用 AHRs 自我中毒导致快速昏迷和高乳酸血症,并完全康复的病例。回顾了相关文献。据我们所知,这是第三例故意 AHRs 中毒报告。3 名患者表现为急性酒精中毒的症状,严重程度取决于摄入的量和速度。
血液酒精水平为 414mg/dl,入院 30 分钟后进行了其他药物检测。血乳酸水平短暂升高至 4.8mmol/L,无肾功能或肝功能障碍。她在 6 小时后恢复了意识,24 小时后拔管并重新入住精神病病房后完全康复。她报告说吞下了整瓶 Aniosgel。
虽然在社交场合(葡萄酒和白酒)过度饮酒会导致血液酒精水平逐渐升高,但 AHRs 中毒通常表现为突然大量摄入酒精。酒精来源的不寻常性质可能导致诊断上的困惑。AHRs 目前有便于大量摄入的瓶装。单位剂量包装或配药可能会降低 AHRs 中毒的风险。