Critical Care Medicine Department, Clinical Center, Bethesda, MD, USA.
Crit Care Med. 2012 Jan;40(1):290-4. doi: 10.1097/CCM.0b013e31822f09c0.
To describe a case of intentional ingestion of hand sanitizer in our hospital and to review published cases and those reported to the American Association of Poison Control Centers' National Poison Data System.
A case report, a literature review of published cases, and a query of the National Poison Data System.
Medical intensive care unit.
Seventeen-yr-old male 37-kg with an intentional ingestion of a hand sanitizer product into his gastrostomy tube.
Intubation, ventilation, and hemodialysis.
Incidence and outcome of reported cases of unintentional and intentional ethanol containing-hand sanitizer ingestion in the United States from 2005 through 2009. A literature search found 14 detailed case reports of intentional alcohol-based hand sanitizer ingestions with one death. From 2005 to 2009, the National Poison Data System received reports of 68,712 exposures to 96 ethanol-based hand sanitizers. The number of new cases increased by an average of 1,894 (95% confidence interval [CI] 1266-2521) cases per year (p =.002). In 2005, the rate of exposures, per year, per million U.S. residents was 33.7 (95% CI 28.4-39.1); from 2005 to 2009, this rate increased on average by 5.87 per year (95% CI 3.70-8.04; p = .003). In 2005, the rate of intentional exposures, per year, per million U.S. residents, was 0.68 (95% CI 0.17-1.20); from 2005 to 2009, this rate increased on average by 0.32 per year (95% CI 0.11-0.53; p = .02).
The number of new cases per year of intentional hand sanitizer ingestion significantly increased during this 5-yr period. Although the majority of cases of hand sanitizer ingestion have a favorable outcome, 288 moderate and 12 major medical outcomes were reported in this National Poison Data System cohort. Increased awareness of the risks associated with intentional ingestion is warranted, particularly among healthcare providers caring for persons with a history of substance abuse, risk-taking behavior, or suicidal ideation.
描述一起在我院发生的手部清洁剂故意摄入病例，并回顾已发表的病例和向美国毒物控制中心国家毒物数据系统报告的病例。
病例报告、已发表病例的文献回顾以及对国家毒物数据系统的查询。
重症监护病房。
17 岁男性，体重 37kg，经胃造口管摄入手部清洁剂产品。
插管、通气和血液透析。
2005 年至 2009 年美国报告的非故意和故意摄入含乙醇手部清洁剂的病例发生率和结局。文献检索发现 14 例详细的酒精基手部清洁剂故意摄入病例，其中 1 例死亡。2005 年至 2009 年，国家毒物数据系统收到 68712 例 96 种乙醇基手部清洁剂暴露报告。新病例数平均每年增加 1894 例（95%置信区间[CI] 1266-2521）（p =.002）。2005 年，美国居民每年每百万人的暴露率为 33.7（95%CI 28.4-39.1）；2005 年至 2009 年，这一比率平均每年增加 5.87（95%CI 3.70-8.04；p =.003）。2005 年，美国居民每年每百万人的故意暴露率为 0.68（95%CI 0.17-1.20）；2005 年至 2009 年，这一比率平均每年增加 0.32（95%CI 0.11-0.53；p =.02）。
5 年间，每年故意摄入手部清洁剂的新病例数显著增加。尽管手部清洁剂摄入的大多数病例结局良好，但该国家毒物数据系统队列中报告了 288 例中度和 12 例严重医疗结局。需要提高对故意摄入相关风险的认识，特别是在照顾有药物滥用、冒险行为或自杀意念史的患者的医护人员中。
