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用于活细胞和组织中硫醇的双光子荧光探针。

A two-photon fluorescent probe for thiols in live cells and tissues.

机构信息

Department of Chemistry, Korea University, 1-Anamdong, Seoul, 136-701, Korea.

出版信息

J Am Chem Soc. 2010 Feb 3;132(4):1216-7. doi: 10.1021/ja9090676.

DOI:10.1021/ja9090676
PMID:20052975
Abstract

We report a two-photon fluorescent probe (ASS) that can be excited by 780 nm femtosecond pulses and detect thiols in live cells and living tissues at a 90-180 microm depth without interference from other biologically relevant species by two-photon microscopy.

摘要

我们报道了一种双光子荧光探针（ASS），它可以用 780nm 的飞秒脉冲激发，通过双光子显微镜在 90-180 微米的深度内无干扰地检测活细胞和活组织中的硫醇，不受其他生物学相关物质的干扰。

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