Phillips W T, Schwartz J G, Blumhardt R, McMahan C A
Department of Radiology, University of Texas Health Science Center, San Antonio 78284-7800.
J Nucl Med. 1991 Mar;32(3):377-81.
We performed a total of 12 gastric emptying studies on 6 normal subjects with a hyperosmolar (1.85 mol/l) 400-kcal glucose solution commonly used for diagnosing diabetes and a more dilute (0.62 mol/l) 200-kcal glucose solution. The gastric half-emptying time was greatly prolonged with both glucose solutions; 107 min for the (1.85 mol/l) 400-kcal glucose solution compared to 66 min for the more dilute (0.62 mol/l) 200-kcal glucose solution. Although the 200-kcal glucose solution contained one-half the amount of glucose (50 g) compared to the 400-kcal solution (100 g), the blood glucose values obtained during a 2-hr period were only slightly lower with the former solution. This study demonstrates significantly delayed gastric emptying of glucose solutions in normal subjects and a linear pattern of gastric emptying formerly associated only with solid meals.
我们对6名正常受试者进行了总共12次胃排空研究，使用的是常用于诊断糖尿病的高渗（1.85摩尔/升）400千卡葡萄糖溶液和更稀的（0.62摩尔/升）200千卡葡萄糖溶液。两种葡萄糖溶液的胃半排空时间均大大延长；（1.85摩尔/升）400千卡葡萄糖溶液为107分钟，而更稀的（0.62摩尔/升）200千卡葡萄糖溶液为66分钟。尽管200千卡葡萄糖溶液所含葡萄糖量（50克）仅为400千卡溶液（100克）的一半，但在2小时期间测得的血糖值，前者仅略低。这项研究表明，正常受试者中葡萄糖溶液的胃排空明显延迟，且胃排空呈现出一种此前仅与固体食物相关的线性模式。
