Vist G E, Maughan R J
Department of Environmental and Occupational Medicine, University Medical School, Foresterhill, Aberdeen, Scotland.
Med Sci Sports Exerc. 1994 Oct;26(10):1269-73.
The purpose of this study was to compare the rate of gastric emptying of 20 g.l-1 (2G), 40 g.l-1 (4G), and 60 g.l-1 (6G) glucose solutions with that of water (W). On separate occasions in randomized order, a 600-ml test solution was instilled into the stomach of each of six healthy male volunteers. Gastric emptying was measured at 10-min intervals for 1 h by a double sampling gastric aspiration method that allowed the volume of test drink and of the gastric secretion present in the stomach to be measured at each time point. All solutions emptied rapidly and followed an exponential emptying pattern. The 20 g.l-1 glucose solution was emptied at the same rate as water. After the first 10 min of rapid emptying, 4G and 6G were emptied slower (P < 0.05) than water. 6G delivered more (P < 0.05) glucose to the small intestine than 4G, and 4G delivered more glucose than 2G. The results indicate that a 20 g.l-1 glucose solution has no effect on gastric emptying compared with water, but that after the first 10 min of rapid emptying, glucose solutions at a concentration of 40 g.l-1 or more delay gastric emptying.
本研究的目的是比较20 g·l-1（2G）、40 g·l-1（4G）和60 g·l-1（6G）葡萄糖溶液与水（W）的胃排空速率。在不同的时间，按照随机顺序，将600毫升测试溶液分别灌入六名健康男性志愿者的胃中。通过双样本胃抽吸法，每隔10分钟测量一次胃排空情况，持续1小时，该方法能够在每个时间点测量胃中测试饮料和胃分泌物的体积。所有溶液排空迅速，且呈现指数排空模式。20 g·l-1葡萄糖溶液的排空速率与水相同。在快速排空的前10分钟后，4G和6G的排空速度比水慢（P<0.05）。6G比4G向小肠输送更多的葡萄糖（P<0.05），4G比2G输送更多的葡萄糖。结果表明，与水相比，20 g·l-1葡萄糖溶液对胃排空没有影响，但在快速排空的前10分钟后，浓度为40 g·l-1或更高的葡萄糖溶液会延迟胃排空。
