Department of Psychology, University of Connecticut, Storrs, CT 06269-1020, USA.
J Autism Dev Disord. 2010 Jul;40(7):787-99. doi: 10.1007/s10803-009-0926-x.
This study investigated the childhood autism rating scale (CARS) as a tool for ASD diagnoses for 2-year-old (n = 376) and 4-year-old (n = 230) children referred for possible autism. The cut-off score to distinguish autistic disorder from PDD-NOS was 32 in the 2-year-old sample (consistent with Lord in J Child Psychol Psychiatry Allied Discipl, 36, 1365-1382, 1995), and 30 in the 4-year-old sample, with good sensitivity and specificity at both ages. The cut-off score to distinguish ASD from non-ASD at both ages was 25.5, with good sensitivity and specificity. Results confirm the utility of the CARS in distinguishing autistic disorder from PDD-NOS, and distinguishing ASD from other developmental disorders and typical development and suggest that an ASD cutoff around 25, which is in common clinical use, is valid.
本研究调查了儿童自闭症评定量表（CARS）作为自闭症谱系障碍（ASD）诊断工具的适用性，评估对象为 2 岁（n = 376）和 4 岁（n = 230）疑似自闭症的儿童。在 2 岁儿童样本中，将自闭症与广泛性发育障碍未特定型（PDD-NOS）区分开来的截断分数为 32（与 Lord 在 J Child Psychol Psychiatry Allied Discipl, 36, 1365-1382, 1995 中的研究结果一致），在 4 岁儿童样本中为 30，在两个年龄段均具有良好的敏感性和特异性。将 ASD 与非 ASD 区分开来的截断分数在两个年龄段均为 25.5，具有良好的敏感性和特异性。结果证实了 CARS 在区分自闭症与 PDD-NOS 以及区分 ASD 与其他发育障碍和典型发育方面的有效性，并表明在临床中常用的 25 左右的 ASD 截断值是有效的。
