患有自闭症谱系障碍的幼儿的诊断稳定性。
Diagnostic stability in very young children with autism spectrum disorders.
作者信息
Kleinman Jamie M, Ventola Pamela E, Pandey Juhi, Verbalis Alyssa D, Barton Marianne, Hodgson Sarah, Green James, Dumont-Mathieu Thyde, Robins Diana L, Fein Deborah
机构信息
Department of Psychology, University of Connecticut, 406 Babbidge Rd., Storrs, CT 06269-1020, USA.
出版信息
J Autism Dev Disord. 2008 Apr;38(4):606-15. doi: 10.1007/s10803-007-0427-8. Epub 2007 Oct 9.
Abstract
Autism Spectrum Disorders (ASD) diagnosis in very young children may be delayed due to doubts about validity. In this study, 77 children received a diagnostic and developmental evaluation between 16 and 35 months and also between 42 and 82 months. Diagnoses based on clinical judgment, Childhood Autism Rating Scale, and the Autism Diagnostic Observation Schedule were stable over time. Diagnoses made using the Autism Diagnostic Interview were slightly less stable. According to clinical judgment, 15 children (19%) moved off the autism spectrum by the second evaluation; none moved onto the spectrum. Results indicate diagnostic stability at acceptable levels for diagnoses made at age 2. Movement off the spectrum may reflect true improvement based on maturation, intervention, or over-diagnosis at age 2.
摘要
由于对有效性存在疑虑，幼儿自闭症谱系障碍（ASD）的诊断可能会延迟。在本研究中，77名儿童在16至35个月以及42至82个月期间接受了诊断和发育评估。基于临床判断、儿童自闭症评定量表和自闭症诊断观察量表的诊断随时间推移较为稳定。使用自闭症诊断访谈做出的诊断稳定性稍差。根据临床判断，到第二次评估时，15名儿童（19%）不再属于自闭症谱系；没有人进入该谱系。结果表明，2岁时做出的诊断在可接受水平上具有诊断稳定性。脱离谱系可能反映了基于成熟、干预或2岁时过度诊断的真正改善。
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本文引用的文献
1
Predictors of optimal outcome in toddlers diagnosed with autism spectrum disorders.
J Autism Dev Disord. 2007 Jan;37(1):98-107. doi: 10.1007/s10803-006-0340-6. Epub 2007 Jan 6.
2
Agreement among four diagnostic instruments for autism spectrum disorders in toddlers.
J Autism Dev Disord. 2006 Oct;36(7):839-47. doi: 10.1007/s10803-006-0128-8.
3
Autism in infancy and early childhood.
Annu Rev Psychol. 2005;56:315-36. doi: 10.1146/annurev.psych.56.091103.070159.
4
Regression and word loss in autistic spectrum disorders.
J Child Psychol Psychiatry. 2004 Jul;45(5):936-55. doi: 10.1111/j.1469-7610.2004.t01-1-00287.x.
5
Autism spectrum disorders: early detection, intervention, education, and psychopharmacological management.
Can J Psychiatry. 2003 Sep;48(8):506-16. doi: 10.1177/070674370304800802.
6
How well does early diagnosis of autism stand the test of time? Follow-up study of children assessed for autism at age 2 and development of an early diagnostic service.
Autism. 2003 Mar;7(1):47-63. doi: 10.1177/1362361303007001005.
7
Practitioner review: Diagnosis of autism spectrum disorder in 2- and 3-year-old children.
J Child Psychol Psychiatry. 2002 Mar;43(3):289-305. doi: 10.1111/1469-7610.00022.
8
A study looking at the effectiveness of developmental screening in identifying learning disabilities in early childhood.
Ir Med J. 2001 May;94(5):148-50.
9
The Modified Checklist for Autism in Toddlers: an initial study investigating the early detection of autism and pervasive developmental disorders.
J Autism Dev Disord. 2001 Apr;31(2):131-44. doi: 10.1023/a:1010738829569.
10
Age and IQ at intake as predictors of placement for young children with autism: a four- to six-year follow-up.
J Autism Dev Disord. 2000 Apr;30(2):137-42. doi: 10.1023/a:1005459606120.
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